| Type | Description |
|---|---|
| Definition | leucine rich repeat and Ig domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:10:00 | LINGO2 rs824248 may serve as a susceptibility marker for gestational diabetes mellitus in Chinese females. | 30426492 |
| 2019-06-08 10:40:00 | These indicate the involvement of LINGO2 in gastric cancer initiation and progression by altering cell motility, stemness, and tumorigenicity. | 30696080 |
| 2015-10-31 10:10:00 | Data indicate that rs10968576, an intronic single nucleotide polymorphism (SNP) within the leucine rich repeat and Ig domain containing 2 LINGO2 (LERN3, LRRN6C) gene was associated with body mass in elderly Swedes at age 70. | 25711307 |
| 2012-10-13 10:59:00 | The results of this study concluded that the LINGO-2 variant rs109668280 does not contribute to the risk of developing parkinson disreas in Taiwan. | 22123311 |
| 2011-07-16 10:36:00 | demonstrated for the first time that rs7033345 is associated with PD and ET and rs10812774 with ET among Asians, suggesting that LINGO2 might act as a susceptibility gene for essential tremor and Parkinson's disease | 21287203 |
| Type | IDs |
|---|---|
| Synonymous | LERN3, LRRN6C |
| Gene |
UniProtKB-ID:
LIGO2_HUMAN
UniprotKB:
Q7L985
UniParc:
UPI000004C7CD
EMBL:
AK290972,
AY358114,
AK172834,
BC137514,
CH471071,
AK056372
Ensembl:
ENSG00000174482
KO:
hsa:158038
|
| Nucleutide sequences |
EMBL-CDS:
BAF83661.1,
EAW58557.1,
BAD18799.1,
AAI37515.1,
BAB71167.1,
AAQ88481.1
Gene_ORFName:
UNQ9234/PRO31993
Ensembl_TRS:
ENST00000308675,
ENST00000613945,
ENST00000379992
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479634,
ENSP00000310126,
ENSP00000369328
RefSeq:
XP_016869792.1,
XP_016869794.1,
XP_016869795.1,
XP_011516026.1,
XP_011516030.1,
NP_001341504.1,
XP_016869796.1,
NP_689783.1,
XP_016869793.1,
NP_001341503.1,
NP_001245211.1
|
| Others |
UniRef100:
UniRef100_Q7L985
UniRef90:
UniRef90_Q7L985
UniRef50:
UniRef50_Q7L985
UniGene:
Hs.662661,
Hs.745029
CCDS:
CCDS6524.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30426492 |
J Cell Physiol Tong Su , Qingxia Ren , Yingying Lu , Wen Tai , Yuan Zhu , Zhengying Li , Juan Wen , Lingmin Hu , Le Zhang , Jiehua Ma |
2019-05-01 | - |
| 30696080 |
Int J Mol Sci Jung Hyun Jo , Soo Been Park , Semi Park , Hee Seung Lee , Chanyang Kim , Dawoon E Jung , Si Young Song |
2019-01-28 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25711307 |
Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes. Mol. Genet. Genomics Mathias Rask-Andersen , Markus Sällman Almén , Lars Lind , Helgi B Schiöth |
2015-08-01 |
LINGO2
|
| 24962325 |
Drug Alcohol Depend Manav Kapoor , Jen-Chyong Wang , Leah Wetherill , Nhung Le , Sarah Bertelsen , Anthony L Hinrichs , John Budde , Arpana Agrawal , Laura Almasy , Kathleen Bucholz , Danielle M Dick , Oscar Harari , Xuei Xiaoling , Victor Hesselbrock , John Kramer , John I Nurnberger , John Rice , Marc Schuckit , Jay Tischfield , Bernice Porjesz , Howard J Edenberg , Laura Bierut , Tatiana Foroud , Alison Goate |
2014-09-01 | - |
| 24390345 |
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature SIGMA Type 2 Diabetes Consortium , Amy L Williams , Suzanne B R Jacobs , Hortensia Moreno-MacÃas , Alicia Huerta-Chagoya , Claire Churchhouse , Carla Márquez-Luna , Humberto GarcÃa-OrtÃz , MarÃa José Gómez-Vázquez , Noël P Burtt , Carlos A Aguilar-Salinas , Clicerio González-Villalpando , Jose C Florez , Lorena Orozco , Christopher A Haiman , Teresa Tusié-Luna , David Altshuler |
2014-02-06 | - |
| 24096698 |
Genome-wide association study of endometrial cancer in E2C2. Hum Genet Immaculata De Vivo , Jennifer Prescott , Veronica Wendy Setiawan , Sara H Olson , Nicolas Wentzensen , Australian National Endometrial Cancer Study Group , John Attia , Amanda Black , Louise Brinton , Chu Chen , Constance Chen , Linda S Cook , Marta Crous-Bou , Jennifer Doherty , Alison M Dunning , Douglas F Easton , Christine M Friedenreich , Montserrat Garcia-Closas , Mia M Gaudet , Christopher Haiman , Susan E Hankinson , Patricia Hartge , Brian E Henderson , Elizabeth Holliday , Pamela L Horn-Ross , David J Hunter , Loic Le Marchand , Xiaolin Liang , Jolanta Lissowska , Jirong Long , Lingeng Lu , Anthony M Magliocco , Mark McEvoy , Tracy A O'Mara , Irene Orlow , Jodie N Painter , Loreall Pooler , Radhai Rastogi , Timothy R Rebbeck , Harvey Risch , Carlotta Sacerdote , Fredrick Schumacher , Rodney J Scott , Xin Sheng , Xiao-ou Shu , Amanda B Spurdle , Deborah Thompson , David Vanden Berg , Noel S Weiss , Lucy Xia , Yong-Bing Xiang , Hannah P Yang , Herbert Yu , Wei Zheng , Stephen Chanock , Peter Kraft |
2014-02-01 | - |
| 23563607 |
Nat. Genet. Sonja I Berndt , Stefan Gustafsson , Reedik Mägi , Andrea Ganna , Eleanor Wheeler , Mary F Feitosa , Anne E Justice , Keri L Monda , Damien C Croteau-Chonka , Felix R Day , Tõnu Esko , Tove Fall , Teresa Ferreira , Davide Gentilini , Anne U Jackson , Jian'an Luan , Joshua C Randall , Sailaja Vedantam , Cristen J Willer , Thomas W Winkler , Andrew R Wood , Tsegaselassie Workalemahu , Yi-Juan Hu , Sang Hong Lee , Liming Liang , Dan-Yu Lin , Josine L Min , Benjamin M Neale , Gudmar Thorleifsson , Jian Yang , Eva Albrecht , Najaf Amin , Jennifer L Bragg-Gresham , Gemma Cadby , Martin den Heijer , Niina Eklund , Krista Fischer , Anuj Goel , Jouke-Jan Hottenga , Jennifer E Huffman , Ivonne Jarick , à sa Johansson , Toby Johnson , Stavroula Kanoni , Marcus E Kleber , Inke R König , Kati Kristiansson , Zoltán Kutalik , Claudia Lamina , Cecile Lecoeur , Guo Li , Massimo Mangino , Wendy L McArdle , Carolina Medina-Gomez , Martina Müller-Nurasyid , Julius S Ngwa , Ilja M Nolte , Lavinia Paternoster , Sonali Pechlivanis , Markus Perola , Marjolein J Peters , Michael Preuss , Lynda M Rose , Jianxin Shi , Dmitry Shungin , Albert Vernon Smith , Rona J Strawbridge , Ida Surakka , Alexander Teumer , Mieke D Trip , Jonathan Tyrer , Jana V Van Vliet-Ostaptchouk , Liesbeth Vandenput , Lindsay L Waite , Jing Hua Zhao , Devin Absher , Folkert W Asselbergs , Mustafa Atalay , Antony P Attwood , Anthony J Balmforth , Hanneke Basart , John Beilby , Lori L Bonnycastle , Paolo Brambilla , Marcel Bruinenberg , Harry Campbell , Daniel I Chasman , Peter S Chines , Francis S Collins , John M Connell , William O Cookson , Ulf de Faire , Femmie de Vegt , Mariano Dei , Maria Dimitriou , Sarah Edkins , Karol Estrada , David M Evans , Martin Farrall , Marco M Ferrario , Jean Ferrières , Lude Franke , Francesca Frau , Pablo V Gejman , Harald Grallert , Henrik Grönberg , Vilmundur Gudnason , Alistair S Hall , Per Hall , Anna-Liisa Hartikainen , Caroline Hayward , Nancy L Heard-Costa , Andrew C Heath , Johannes Hebebrand , Georg Homuth , Frank B Hu , Sarah E Hunt , Elina Hyppönen , Carlos Iribarren , Kevin B Jacobs , John-Olov Jansson , Antti Jula , Mika Kähönen , Sekar Kathiresan , Frank Kee , Kay-Tee Khaw , Mika Kivimäki , Wolfgang Koenig , Aldi T Kraja , Meena Kumari , Kari Kuulasmaa , Johanna Kuusisto , Jaana H Laitinen , Timo A Lakka , Claudia Langenberg , Lenore J Launer , Lars Lind , Jaana Lindström , Jianjun Liu , Antonio Liuzzi , Marja-Liisa Lokki , Mattias Lorentzon , Pamela A Madden , Patrik K Magnusson , Paolo Manunta , Diana Marek , Winfried März , Irene Mateo Leach , Barbara McKnight , Sarah E Medland , Evelin Mihailov , Lili Milani , Grant W Montgomery , Vincent Mooser , Thomas W Mühleisen , Patricia B Munroe , Arthur W Musk , Narisu Narisu , Gerjan Navis , George Nicholson , Ellen A Nohr , Ken K Ong , Ben A Oostra , Colin N A Palmer , Aarno Palotie , John F Peden , Nancy Pedersen , Annette Peters , Ozren Polasek , Anneli Pouta , Peter P Pramstaller , Inga Prokopenko , Carolin Pütter , Aparna Radhakrishnan , Olli Raitakari , Augusto Rendon , Fernando Rivadeneira , Igor Rudan , Timo E Saaristo , Jennifer G Sambrook , Alan R Sanders , Serena Sanna , Jouko Saramies , Sabine Schipf , Stefan Schreiber , Heribert Schunkert , So-Youn Shin , Stefano Signorini , Juha Sinisalo , Boris Skrobek , Nicole Soranzo , Alena StanÄáková , Klaus Stark , Jonathan C Stephens , Kathleen Stirrups , Ronald P Stolk , Michael Stumvoll , Amy J Swift , Eirini V Theodoraki , Barbara Thorand , David-Alexandre Tregouet , Elena Tremoli , Melanie M Van der Klauw , Joyce B J van Meurs , Sita H Vermeulen , Jorma Viikari , Jarmo Virtamo , Veronique Vitart , Gérard Waeber , Zhaoming Wang , Elisabeth Widén , Sarah H Wild , Gonneke Willemsen , Bernhard R Winkelmann , Jacqueline C M Witteman , Bruce H R Wolffenbuttel , Andrew Wong , Alan F Wright , M Carola Zillikens , Philippe Amouyel , Bernhard O Boehm , Eric Boerwinkle , Dorret I Boomsma , Mark J Caulfield , Stephen J Chanock , L Adrienne Cupples , Daniele Cusi , George V Dedoussis , Jeanette Erdmann , Johan G Eriksson , Paul W Franks , Philippe Froguel , Christian Gieger , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Christian Hengstenberg , Andrew A Hicks , Aroon Hingorani , Anke Hinney , Albert Hofman , Kees G Hovingh , Kristian Hveem , Thomas Illig , Marjo-Riitta Jarvelin , Karl-Heinz Jöckel , Sirkka M Keinanen-Kiukaanniemi , Lambertus A Kiemeney , Diana Kuh , Markku Laakso , Terho Lehtimäki , Douglas F Levinson , Nicholas G Martin , Andres Metspalu , Andrew D Morris , Markku S Nieminen , Inger Njølstad , Claes Ohlsson , Albertine J Oldehinkel , Willem H Ouwehand , Lyle J Palmer , Brenda Penninx , Chris Power , Michael A Province , Bruce M Psaty , Lu Qi , Rainer Rauramaa , Paul M Ridker , Samuli Ripatti , Veikko Salomaa , Nilesh J Samani , Harold Snieder , Thorkild I A Sørensen , Timothy D Spector , Kari Stefansson , Anke Tönjes , Jaakko Tuomilehto , André G Uitterlinden , Matti Uusitupa , Pim van der Harst , Peter Vollenweider , Henri Wallaschofski , Nicholas J Wareham , Hugh Watkins , H-Erich Wichmann , James F Wilson , Goncalo R Abecasis , Themistocles L Assimes , Inês Barroso , Michael Boehnke , Ingrid B Borecki , Panos Deloukas , Caroline S Fox , Timothy Frayling , Leif C Groop , Talin Haritunian , Iris M Heid , David Hunter , Robert C Kaplan , Fredrik Karpe , Miriam F Moffatt , Karen L Mohlke , Jeffrey R O'Connell , Yudi Pawitan , Eric E Schadt , David Schlessinger , Valgerdur Steinthorsdottir , David P Strachan , Unnur Thorsteinsdottir , Cornelia M van Duijn , Peter M Visscher , Anna Maria Di Blasio , Joel N Hirschhorn , Cecilia M Lindgren , Andrew P Morris , David Meyre , André Scherag , Mark I McCarthy , Elizabeth K Speliotes , Kari E North , Ruth J F Loos , Erik Ingelsson |
2013-05-01 | - |
| 23382691 |
PLoS Genet Gordan Lauc , Jennifer E Huffman , Maja PuÄiÄ , Lina Zgaga , Barbara Adamczyk , Ana MužiniÄ , Mislav Novokmet , Ozren PolaÅ¡ek , Olga Gornik , Jasminka KriÅ¡tiÄ , Toma Keser , Veronique Vitart , Blanca Scheijen , Hae-Won Uh , Mariam Molokhia , Alan Leslie Patrick , Paul McKeigue , Ivana KolÄiÄ , Ivan KreÅ¡imir LukiÄ , Olivia Swann , Frank N van Leeuwen , L Renee Ruhaak , Jeanine J Houwing-Duistermaat , P Eline Slagboom , Marian Beekman , Anton J M de Craen , André M Deelder , Qiang Zeng , Wei Wang , Nicholas D Hastie , Ulf Gyllensten , James F Wilson , Manfred Wuhrer , Alan F Wright , Pauline M Rudd , Caroline Hayward , Yurii Aulchenko , Harry Campbell , Igor Rudan |
2013-01-01 | - |
| 22123311 |
LINGO-2 polymorphism and the risk of Parkinson's disease in Taiwan. Parkinsonism Relat. Disord. Feng-Chieh Su , Chiung-Mei Chen , Yi-Chun Chen , Yih-Ru Wu |
2012-06-01 |
LINGO2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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