| Type | Description |
|---|---|
| Definition | adenylosuccinate lyase |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 10:50:00 | Adenylosuccinate lyase (ADSL) is an EglN2 hydroxylase substrate in triple negative breast cancer. | 31729379 |
| 2019-12-07 11:11:00 | ADSL undergoes conformational changes during catalysis which, together with the crystal structure of a hitherto undetermined product bound conformation, explains the molecular origin of disease for several modern human ADSL mutants. | 30573755 |
| 2019-03-09 12:51:00 | involved in endometrial cancer aggressiveness by regulating expression of killer cell lectin-like receptor C3 | 29467457 |
| 2014-04-12 10:21:00 | Case Report: Malaysian patient compound heterozygous for two novel ADSL mutations giving rise to adenylosuccinate lyase deficiency. | 20177786 |
| 2013-08-31 10:13:00 | Missense mutations in the adenylosuccinate lyase is associated with Adenylosuccinate lyase deficiency, an inborn error of purine metabolism characterized by neurological and physiological symptoms. | 23714113 |
| Type | IDs |
|---|---|
| Synonymous | AMPS, ASASE, ASL |
| Gene |
UniProtKB-ID:
PUR8_HUMAN,
X5D8S6_HUMAN,
X5D7W4_HUMAN
UniprotKB:
P30566,
X5D8S6,
X5D7W4
UniParc:
UPI000002B1F2,
UPI000443728E,
UPI0000132AC7
EMBL:
S60710,
KJ535056,
BC000253,
X65867,
CR456368,
AL022238,
AF067854,
AF067853,
CH471095,
KJ534763
Ensembl:
ENSG00000239900
KO:
hsa:158
|
| Nucleutide sequences |
EMBL-CDS:
AAC60603.1,
CAA46697.1,
CAA46696.1,
AAC21561.1,
AAC21560.1,
EAW60375.1,
AAH00253.1,
CAG30254.1,
EAW60376.1,
AHW56403.1,
AHW56695.1
Gene_ORFName:
hCG_40060
Ensembl_TRS:
ENST00000342312,
ENST00000623063
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341429,
ENSP00000485525
RefSeq:
XP_011528279.1,
XP_016884125.1,
XP_016884126.1,
NP_001350769.1,
XP_016884128.1,
NP_001116850.1,
XP_011528282.1,
XP_024307934.1,
NP_001304852.1,
NP_000017.1,
XP_016884129.1,
XP_016884127.1
|
| Others |
UniRef100:
UniRef100_P30566,
UniRef100_X5D7W4
UniRef90:
UniRef90_X5D7W4,
UniRef90_P30566
UniRef50:
UniRef50_X5D7W4,
UniRef50_P30566
UniGene:
Hs.75527
CCDS:
CCDS14001.1,
CCDS46714.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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