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1579 CYP4A11

1579

CYP4A11

cytochrome P450 family 4 subfamily A member 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytochrome P450 family 4 subfamily A member 11

研究结论

Date Results Publications
2020-12-05 12:58:00 CYP4A11 is involved in the development of nonalcoholic fatty liver disease via lipid peroxidation and inflammation. 32124935
2020-07-11 11:03:00 Mutation in CYP4A11 gene is associated with cetuximab resistance in colorectal cancer. 32141150
2019-07-20 10:12:00 The rs1126742 T/C polymorphism of CYP4A11 is more likely to be a genetic risk factor for the hypertension cases in the Caucasian population. Moreover, whereas the AG genotype of CYP4A11 rs9332978 may be associated with an increased risk of hypertension, the AA genotype of rs9333025 may be linked to a decreased risk of cardiovascular and cerebrovascular diseases. [meta-analysis] 30132788
2018-09-08 10:08:00 Haplotype G-C-A of CYP4A11 was associated with increased risk of coronary artery disease. 29484037
2018-03-17 10:13:00 Gene-gene interaction between rs1126742 and rs3890011 and gene-environment interaction between rs1126742 and smoking were associated with increased EH risk. 28534704

名称对应

Type IDs
Synonymous CP4Y, CYP4A2, CYP4AII, CYPIVA11
Gene
UniProtKB-ID: CP4AB_HUMAN
UniprotKB: Q02928
UniParc: UPI00001281E4, UPI0001761630
EMBL: X71480, AF525488, L04751, AY369778, S67580, S67581, BC041158, AL731892, D26481
Ensembl: ENSG00000187048
KO: hsa:1579
Nucleutide sequences
EMBL-CDS: AAH41158.1, AAA58436.1, AAB29503.1, AAQ56847.1, CAA50586.1, AAB29502.1, AAO16078.1, BAA05491.1
Ensembl_TRS: ENST00000310638
Protein sequencees
Ensembl_PRO: ENSP00000311095
RefSeq: XP_016855954.1, NP_000769.2, NP_001350516.1, NP_001306084.1, XP_005270596.1
Others
UniRef100: UniRef100_Q02928
UniRef90: UniRef90_Q02928
UniRef50: UniRef50_Q02928
UniGene: Hs.1645, Hs.726474
CCDS: CCDS543.1

全选

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