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157848 NKX6-3

157848

NKX6-3

NK6 homeobox 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition NK6 homeobox 3

研究结论

Date Results Publications
2019-10-19 11:25:00 These results indicate that NKX6.3 depletion in gastric epithelial cells activates AICDA/APOBEC family, leading to accumulation of genetic mutations and eventually driving the development of gastric cancers. 30514953
2019-04-06 12:12:00 These results identify genetic variants associated with the efficacy of weight loss in obese subjects and identify a role for NKX6.3 in lipid metabolism, and thereby possibly weight control. 30710084
2019-02-23 11:02:00 NKX6.3 inhibits gastric mucosal atrophy by regulating amyloid beta accumulation and inflammatory reaction in gastric epithelial cells. 30686901
2018-12-22 10:37:00 these results suggest that NKX6.3 inhibits production by inducing the expression of Hace1 via down-regulating NF-kB and DNMT1 activity in gastric epithelial cells. 28584243
2017-02-25 12:13:00 The expression level of NKX6.3 is involved in regulation of gastric cancer progression and expression of Wnt/beta-catenin and Rho-GTPase pathway-related genes in clinical samples. 27333045

名称对应

Type IDs
Synonymous NKX6.3
Gene
UniProtKB-ID: NKX63_HUMAN
UniprotKB: A6NJ46
UniParc: UPI0000DBEF21, UPI000006EB2C
EMBL: CH471080, AC113133, AK057898
Ensembl: ENSG00000165066
KO: hsa:157848
Nucleutide sequences
EMBL-CDS: BAB71610.1, EAW63252.1, EAW63251.1
Ensembl_TRS: ENST00000518699, ENST00000524115
Protein sequencees
Ensembl_PRO: ENSP00000428361, ENSP00000429553
RefSeq: NP_689781.1, NP_001351770.1
Others
UniRef100: UniRef100_A6NJ46
UniRef90: UniRef90_A6NJ46
UniRef50: UniRef50_A6NJ46
UniGene: Hs.647132
CCDS: CCDS6118.1

全选

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研究热度

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