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157506 RDH10

157506

RDH10

retinol dehydrogenase 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition retinol dehydrogenase 10

研究结论

Date Results Publications
2020-04-11 11:48:00 RDH10 regulated the migration and invasion of glioma cells via the TGF-beta/SMAD signaling pathway. 31613821
2019-02-23 10:03:00 increased expression of ALDH1A1-RDH10-RARalpha- PPARbeta/delta pattern could be considered as adverse prognostic factor associated with a higher concentration of paraprotein and worst overall survival of patients with newly diagnosed multiple myeloma. 30695588
2017-12-02 11:32:00 In close proximity to RDH10 gene on human chromosome 8 are located two genes that are phylogenetically related to RDH10. The predicted protein products of these genes, retinol dehydrogenase epidermal 2 (RDHE2, SDR16C5) and retinol dehydrogenase epidermal 2-similar (RDHE2S, SDR16C6), share 59% and 56% sequence similarity with RDH10. 27793605
2017-06-03 12:18:00 the bifunctional nature of retinoid oxidoreductase complex provides the RA-based signaling system with robustness by safeguarding appropriate RA concentration despite naturally occurring fluctuations in RDH10 and DHRS3. 28232491
2017-05-20 12:47:00 Taken together, our findings demonstrate that RDH10 is essential during the early stages of facial morphogenesis for the formation of a functional nasal airway, and furthermore establish Rdh10 mutant mice as an important model system to study choanal atresia (CA) . 28169399

名称对应

Type IDs
Synonymous SDR16C4
Gene
UniProtKB-ID: RDH10_HUMAN, A0A024R7X6_HUMAN
UniprotKB: Q8IZV5, A0A024R7X6
UniParc: UPI0000054C83
EMBL: BC067131, AY358270, AF456765, CH471068
Ensembl: ENSG00000121039
KO: hsa:157506
Nucleutide sequences
EMBL-CDS: AAH67131.1, AAN64747.1, AAQ88637.1, EAW87002.1, EAW87001.1
Gene_ORFName: UNQ9375/PRO34191, hCG_19185
Ensembl_TRS: ENST00000240285
Protein sequencees
Ensembl_PRO: ENSP00000240285
RefSeq: NP_742034.1
Others
UniRef100: UniRef100_Q8IZV5
UniRef90: UniRef90_Q8VCH7
UniRef50: UniRef50_Q8VCH7
UniGene: Hs.244940
CCDS: CCDS6213.1

全选

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