| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:21:00 | Dissecting the roles of GRK2 and GRK3 in mu-opioid receptor internalization and beta-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells. | 33060647 |
| 2020-07-25 12:37:00 | RKIP has several binding sites within the N-termini of GRK3.The N-termini of GRK3 binds to beta2-adrenoceptors. | 31604529 |
| 2018-09-15 10:08:00 | Study found that GRK3 was significantly overexpressed in 162 pairs of colon cancer tissues than in the matched noncancerous mucosa. These data show that aberrant expression of GRK3 plays an important role in promoting colon cancer progression through enhanced proliferation and reduced apoptosis. | 29445249 |
| 2018-09-01 11:15:00 | hat expression of GRK3 was down-regulated in pancreatic ductal adenocarcinoma and was an independent prognostic factor | 29254792 |
| 2018-02-10 11:24:00 | GRK3 is a new critical activator of neuroendocrine phenotypes and mediator of CREB activation in promoting neuroendocrine differentiation of prostate cancer cells. | 27191986 |
| Type | IDs |
|---|---|
| Synonymous | ADRBK2, BARK2 |
| Gene |
UniProtKB-ID:
ARBK2_HUMAN,
A0A024R1D8_HUMAN,
Q8N433_HUMAN
UniprotKB:
P35626,
A0A024R1D8,
Q8N433
UniParc:
UPI0000050EDB,
UPI000007250E
EMBL:
X69117,
AL022329,
CH471095,
BC036797
Ensembl:
ENSG00000100077
KO:
hsa:157
|
| Nucleutide sequences |
EMBL-CDS:
CAA48870.1,
EAW59700.1,
EAW59699.1,
AAH36797.1
Gene_ORFName:
hCG_40095
Ensembl_TRS:
ENST00000324198,
ENST00000619906
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000317578,
ENSP00000478925
RefSeq:
NP_005151.2,
XP_011528277.1,
NP_001349707.1
|
| Others |
UniRef100:
UniRef100_P35626
UniRef90:
UniRef90_P35626
UniRef50:
UniRef50_P26817
UniGene:
Hs.657494
CCDS:
CCDS13832.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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