| Type | Description |
|---|---|
| Definition | hyaluronoglucosaminidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 13:08:00 | Mice deficient in HYAL2 are more susceptible to an acute model of colitis, and this increased susceptibility is abrogated by transfusion of HYAL2-competent platelets. | 31262781 |
| 2019-03-02 11:27:00 | Knockdown of Hyal2 in articular cartilage induced osteoarthritis development and progression possibly mediated by an imbalance of hyaluronan metabolism. | 28765635 |
| 2017-11-04 10:41:00 | Hyal2(-/-) mice have increased hyaluronan, which may promote endothelial-to-mesenchymal transition and proliferation of mesenchymal cells leading to congenital heart defects and heart failure. | 28196902 |
| 2017-08-19 11:40:00 | It was concluded that: HYAL1 and HYAL2 are both needed for tissue HA catabolism; 2) HYAL2 is required for high MW HA clearance in lymph nodes and plasma and for HA endocytosis by liver NPCs; and 3) the main role of HYAL1 is HA degradation within liver NPCs. | 26887442 |
| 2017-05-27 10:55:00 | Hyal2-/- mice present craniofacial abnormalities, including submucosal cleft palate and incompletely penetrant cor triatriatum sinister with hearing loss. | 28081210 |
| Type | IDs |
|---|---|
| Synonymous | AI256841, AU020858, AW555733 |
| Gene |
UniProtKB-ID:
HYAL2_MOUSE,
Q3UZE4_MOUSE
UniprotKB:
O35632,
Q3UZE4
UniParc:
UPI0000021172
EMBL:
AJ000059,
AF302844,
AJ000060,
AK133886,
AF422177,
AF302843
Ensembl:
ENSMUSG00000010047
KO:
mmu:15587
|
| Nucleutide sequences |
EMBL-CDS:
AAK28482.1,
CAA03889.1,
AAK28481.1,
AAL17823.1,
CAA03888.1,
BAE21913.1
Ensembl_TRS:
ENSMUST00000010191,
ENSMUST00000195752
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000141280,
ENSMUSP00000010191
RefSeq:
XP_006511707.1,
NP_034619.2,
XP_006511706.1,
XP_036010506.1
|
| Others |
UniRef100:
UniRef100_O35632
UniRef90:
UniRef90_O35632
UniRef50:
UniRef50_Q12891
UniGene:
Mm.4834,
Mm.440982
CCDS:
CCDS23496.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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