| Type | Description |
|---|---|
| Definition | hyaluronoglucosaminidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 11:40:00 | It was concluded that: HYAL1 and HYAL2 are both needed for tissue HA catabolism; 2) HYAL2 is required for high MW HA clearance in lymph nodes and plasma and for HA endocytosis by liver NPCs; and 3) the main role of HYAL1 is HA degradation within liver NPCs. | 26887442 |
| 2017-06-10 12:12:00 | Findings suggest that HYAL1 contributes to endothelial and glycocalyx dysfunction induced by diabetes. HYAL1 inhibitors could be explored as a new therapeutic approach to prevent vascular complications in diabetes. | 27246914 |
| 2015-09-26 21:42:00 | HYAL1 is necessary for the breakdown of intracellular HA in the cortex, whereas HYAL2 is essential for the degradation of extracellular HA in all kidney regions | 25468725 |
| 2014-12-20 12:39:00 | The activity of the processed form of Hyal-1 was largely underestimated. | 24502338 |
| 2014-06-28 13:45:00 | The knockdown of Hyal-1 results in an 80% decrease of total acid hyaluronidase activity in the mouse liver, confirming that Hyal-1 is a key actor of hyaluronic acid catabolism in this organ. | 24667601 |
| Type | IDs |
|---|---|
| Synonymous | Fus2, Hya1, Hyal-1, Nat6 |
| Gene |
UniProtKB-ID:
HYAL1_MOUSE
UniprotKB:
Q91ZJ9
UniParc:
UPI0000021174,
UPI00000E917B
EMBL:
AF417498,
AF422176,
AL672219,
AF069741,
AF417496,
AF011567,
AK028942,
AF338323,
BC021636,
AF417497
Ensembl:
ENSMUSG00000010051
KO:
mmu:15586
|
| Nucleutide sequences |
EMBL-CDS:
BAC26206.1,
AAL57173.1,
AAM14432.1,
AAL17822.1,
AAH21636.1,
AAM14428.1,
AAL54881.1,
AAC15949.1,
AAM14430.1
Ensembl_TRS:
ENSMUST00000010195,
ENSMUST00000112387
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000010195,
ENSMUSP00000108006
RefSeq:
NP_032343.3,
NP_001318090.2
|
| Others |
UniRef100:
UniRef100_Q91ZJ9
UniRef90:
UniRef90_Q91ZJ9
UniRef50:
UniRef50_Q91ZJ9
UniGene:
Mm.475658
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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