| Type | Description |
|---|---|
| Definition | Vpr |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137. | 32538781 |
| 2021-04-03 13:34:00 | HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-kappaB/IRF3 nuclear transport. | 33300875 |
| 2020-11-21 13:19:00 | HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing. | 31511615 |
| 2020-04-11 10:08:00 | The data demonstrate that during HIV-1 infection of CD4 T cells, incoming Vpr acts to inhibit the autophagy process activated during viral entry to 'prepare' the cells for an ef fi cient viral replication by decreasing the expression of three autophagy proteins: LC3, Beclin-1 and BNIP3, at their transcriptional level. | 31628772 |
| 2020-03-21 10:39:00 | data imply that HIV-1 Vpr uses additional, yet to be identified mechanisms to facilitate HIV-1 replication in T cells. | 31019079 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
A0A288CFT1_HV1H2
UniprotKB:
A0A288CFT1
UniParc:
UPI00000134EE
EMBL:
AF033819
KO:
vg:155807
|
| Nucleutide sequences |
EMBL-CDS:
AAC82595.1
|
| Protein sequencees |
RefSeq:
NP_057852.2
|
| Others |
UniRef100:
UniRef100_P69725
UniRef90:
UniRef90_P69725
UniRef50:
UniRef50_P69725
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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