| Type | Description |
|---|---|
| Definition | 5-hydroxytryptamine (serotonin) receptor 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | Dynamic interactions of the 5-HT6 receptor with protein partners control dendritic tree morphogenesis. | 32047117 |
| 2019-07-13 10:41:00 | Intracellular 5-hydroxytryptamine receptors (5-HT6R) signaling was found to be linked to RhoA GTPase activation and was involved in the maturation of osteoclasts. This signaling pathway also showed enhanced bone destruction after lipopolysaccharide (LPS) administration in mice. | 29896304 |
| 2019-02-23 10:58:00 | Results suggest that degeneration of the nigrostriatal pathway causes the decreased dopamine levels in the limbic and limbic related brain regions and the enhanced sensitivity of the 5-HT6 receptor on the glutamate and GABA neurons in the basolateral amygdala, which appear to be an etiologic and pathophysiological factor for anxiety in Parkinson's disease. | 29778944 |
| 2018-06-30 11:36:00 | High 5-HT6R expression is associated with delayed bone development and regeneration. | 27581523 |
| 2018-05-19 11:20:00 | This study suggested that 5-HT6 plays a critical role in Alzheimer's disease development through regulating the morphology and function of neuronal primary cilia, which is possibly related to the AIS and axon alterations in Alzheimer's disease development. | 28931427 |
| Type | IDs |
|---|---|
| Synonymous | 5-HT6 |
| Gene |
UniProtKB-ID:
5HT6R_MOUSE,
Q14AW8_MOUSE
UniprotKB:
Q9R1C8,
Q14AW8
UniParc:
UPI0000022FA7
EMBL:
AF134158,
BC116652,
BC116653
Ensembl:
ENSMUSG00000028747
|
| Nucleutide sequences |
EMBL-CDS:
AAD46490.1,
AAI16653.1,
AAI16654.1
Ensembl_TRS:
ENSMUST00000068036,
ENSMUST00000105802
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068333,
ENSMUSP00000101428
RefSeq:
NP_001364025.1,
NP_067333.1
|
| Others |
UniRef100:
UniRef100_Q9R1C8
UniRef90:
UniRef90_Q9R1C8
UniRef50:
UniRef50_P31388
UniGene:
Mm.291096
CCDS:
CCDS18838.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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