| Type | Description |
|---|---|
| Definition | 5-hydroxytryptamine (serotonin) receptor 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:25:00 | Serotonin receptors 5-HTR2A and 5-HTR2B are involved in cigarette smoke-induced airway inflammation, mucus hypersecretion and airway remodeling in mice. | 31787571 |
| 2020-11-21 13:20:00 | Differential allosteric modulation within dopamine D2R - neurotensin NTS1R and D2R - serotonin 5-HT2AR receptor complexes gives bias to intracellular calcium signalling. | 31704949 |
| 2020-06-27 10:58:00 | Evidence for a molecular basis of gene-environmental interactions was identified in antisocial behavior models and early-life 5-HT2A receptor activation following stress. | 30716416 |
| 2020-05-23 11:36:00 | Study shows that sustained activation of postsynaptic 5-HT2A receptors gates plasticity at prefrontal cortex synapses. findings provide one of the first examples of LTD gating under the control of a G protein-coupled receptor that might lead to imbalanced synaptic plasticity and memory impairment following a nonphysiological elevation of extracellular serotonin. | 29917056 |
| 2019-12-28 10:51:00 | Peripheral serotonin causes dengue virus-induced thrombocytopenia through 5HT2 receptors. | 30755421 |
| Type | IDs |
|---|---|
| Synonymous | 5-HT-2, 5-HT-2A, E030013E04, Htr-2, Htr2 |
| Gene |
UniProtKB-ID:
5HT2A_MOUSE,
Q543D4_MOUSE
UniprotKB:
P35363,
Q543D4
UniParc:
UPI00000040D4
EMBL:
AK053140,
BC108972,
S49542,
BC108973
Ensembl:
ENSMUSG00000034997
KO:
mmu:15558
|
| Nucleutide sequences |
EMBL-CDS:
AAB24369.1,
AAI08973.1,
AAI08974.1,
BAC35279.1
Ensembl_TRS:
ENSMUST00000036653
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047774
RefSeq:
NP_766400.1
|
| Others |
UniRef100:
UniRef100_P35363
UniRef90:
UniRef90_P28223
UniRef50:
UniRef50_P28223
UniGene:
Mm.214351
CCDS:
CCDS27275.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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