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15551 Htr1b

15551

Htr1b

5-hydroxytryptamine (serotonin) receptor 1B

protein-coding

Mus musculus

基因描述

Type Description
Definition 5-hydroxytryptamine (serotonin) receptor 1B

研究结论

Date Results Publications
2017-12-02 12:15:00 Consistent with previous studies that have optogenetically inhibited vHPC-mPFC projections, activating prefrontal 5-HT1B receptors suppressed theta-frequency mPFC activity (4-12 Hz), and reduced avoidance of anxiogenic regions in the elevated plus maze 27974203
2017-09-16 12:33:00 we showed that gravity changes induced differential modulation of gene expression of BDNF and 5-HTRs (5-HT1AR, 5-HT1BR and 5-HT2AR) in some brain regions. The modulation of gene expression may constitute molecular bases that underlie behavioral alteration induced by gravity changes. 28591153
2017-09-16 11:04:00 Mice lacking 5-HT1B autoreceptors displayed the expected increases in extracellular serotonin levels in the ventral hippocampus following administration of a selective serotonin reuptake inhibitor. 27353308
2017-07-15 10:57:00 5-HT1B receptor-dependent cellular Src-related kinase-Nox1-pathways contribute to vascular remodeling in pulmonary arterial hypertension. 28473438
2016-08-27 12:49:00 Data suggest that pharmacological stimulation of serotonin 5Ht1b receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1) induced by Dpp4 (dipeptidylpeptidase 4) inhibition independently of feeding and also improves glucose tolerance. 26234524

名称对应

Type IDs
Synonymous 5-HT-1B
Gene
UniProtKB-ID: 5HT1B_MOUSE, Q0VES5_MOUSE
UniprotKB: P28334, Q0VES5
UniParc: UPI00000268D8
EMBL: BC131951, M85151, Z11597, BC119129
Ensembl: ENSMUSG00000049511
KO: mmu:15551
Nucleutide sequences
EMBL-CDS: CAA77678.1, AAA83221.1, AAI31952.1, AAI19130.1
Ensembl_TRS: ENSMUST00000051005, ENSMUST00000183482
Protein sequencees
Ensembl_PRO: ENSMUSP00000050898, ENSMUSP00000139389
RefSeq: XP_030099923.1, NP_034612.1
Others
UniRef100: UniRef100_P28334
UniRef90: UniRef90_P28222
UniRef50: UniRef50_P28222
UniGene: Mm.445308
CCDS: CCDS23370.1

全选

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