| Type | Description |
|---|---|
| Definition | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 11:43:00 | Transplant of donor allografts with conditional Ndst1 deficiency exhibit significantly reduced acute rejection, comparable to systemic chemokine-GAG inhibition. Modified disaccharides in engrafted organs correlate with reduced rejection. | 30194334 |
| 2019-03-09 12:19:00 | Tubulo-interstitial macrophage influx and fibrosis are reduced by endothelial Ndst1 deficiency in experimental diabetes. | 29330473 |
| 2019-02-09 10:30:00 | An essential role for Heparin sulfate proteoglycan sulfation via NDST1,2,3 in modulating signal transduction during mouse implantation. | 29688404 |
| 2017-07-01 12:42:00 | Podocyte-glomerular basement membrane interactions and cytoskeletal organization are disrupted in the glomeruli of the Ndst1-/- mutant mouse model | 26936875 |
| 2014-10-04 10:46:00 | Although the renal phenotype of the Ndst1(-/-) mouse is mild, the data show that heparan chain N-sulfation plays a key role in podocyte organization. | 23924956 |
| Type | IDs |
|---|---|
| Synonymous | 1200015G06Rik, HSNST, HSNST 1, Hsst, N-HSST, N-HSST 1, NDST-1, b2b2230Clo |
| Gene |
UniProtKB-ID:
NDST1_MOUSE
UniprotKB:
Q3UHN9
UniParc:
UPI00005B2753,
UPI00000294DC,
UPI00000EA42B
EMBL:
AF049894,
AK171013,
BC066098,
AK035642,
AF074926,
AK170041,
AK147282,
BC079561
Ensembl:
ENSMUSG00000054008
KO:
mmu:15531
|
| Nucleutide sequences |
EMBL-CDS:
BAE41527.1,
AAD15980.1,
AAH66098.1,
BAE42184.1,
AAH79561.1,
AAC17228.1,
BAE27818.1,
BAC29136.1
Ensembl_TRS:
ENSMUST00000237783,
ENSMUST00000169273
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158312,
ENSMUSP00000126623
RefSeq:
XP_036016885.1,
NP_001335031.1,
XP_030106202.1,
XP_030106201.1,
XP_006525736.1,
NP_032332.2,
XP_030106200.1,
XP_006525731.1,
XP_036016887.1,
NP_001335029.1,
XP_036016884.1,
NP_001335030.1,
NP_001335032.1,
NP_001335075.1,
XP_036016886.1
|
| Others |
UniRef100:
UniRef100_Q3UHN9
UniRef90:
UniRef90_Q3UHN9
UniRef50:
UniRef50_Q3UHN9
UniGene:
Mm.181862,
Mm.486185
CCDS:
CCDS37834.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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