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15502 Dnaja1

15502

Dnaja1

DnaJ heat shock protein family (Hsp40) member A1

protein-coding

Mus musculus

基因描述

Type Description
Definition DnaJ heat shock protein family (Hsp40) member A1

研究结论

Date Results Publications
2020-01-25 10:18:00 Our results show that farnesylated DNAJA1 is a crucial chaperone in maintaining mutant p53 stabilization and targeting farnesylated DNAJA1 by atorvastatin will be critical for inhibiting p53 mutant cancer. 31397499
2012-03-31 11:14:00 DnaJa1 farnesylation is required to maintain, and farnesyltransferase inhibition reduces, AID protein levels in B cells. Thus, DnaJa1 is a limiting factor that plays a non-redundant role in the functional stabilization of AID 22085931
2010-06-28 11:58:00 Hsc70 and a dimer of DjA1 independently bind to an unfolded protein 20363747
2010-01-21 00:00:00 Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. 15661747
2010-01-21 00:00:00 HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor 11809754

名称对应

Type IDs
Synonymous HSJ-2, Hsj2, Nedd7
Gene
UniProtKB-ID: DNJA1_MOUSE, Q5NTY0_MOUSE
UniprotKB: P63037, Q5NTY0
UniParc: UPI0000004163
EMBL: AB183426, AK167212, BC057876, AK145963, AF055664, BC158024, AK083046
Ensembl: ENSMUSG00000028410
KO: mmu:15502
Nucleutide sequences
EMBL-CDS: AAH57876.1, BAC38744.1, AAC78597.1, BAE39339.1, BAE26788.1, AAI58025.1, BAD82815.1
Ensembl_TRS: ENSMUST00000030118, ENSMUST00000164233
Protein sequencees
Ensembl_PRO: ENSMUSP00000129730, ENSMUSP00000030118
RefSeq: NP_001158143.1, NP_032324.1, NP_001158144.1
Others
UniRef100: UniRef100_P63037
UniRef90: UniRef90_P31689
UniRef50: UniRef50_P31689
UniGene: Mm.27897
CCDS: CCDS18049.1

全选

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