| Type | Description |
|---|---|
| Definition | complement factor H |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 10:50:00 | enhancive miR-146a could upregulate the expression of IL-1beta and downregulate the expression of CFH, whereas reductive miR-146a could downregulate the expression of IL-1beta and upregulate the expression of CFH, in hippocampi of chronic temporal lobe epilepsy rat models. | 29590637 |
| 2017-12-23 12:43:00 | These findings suggest that immunopathological deficits associated with temporal lobe epilepsy (TLE) can in part be explained by a generalized miR-146a-mediated down-regulation of CFH that may contribute to epileptogenesis in a rat model of TLE. | 27852797 |
| 2012-11-24 10:38:00 | Factor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate. | 22815489 |
| 2010-01-21 00:00:00 | expression and regulation in cultured heptocytes, Kupffer cells, and hepatoma cell lines | 11850531 |
| 2010-01-21 00:00:00 | Glomerular epithelial cells(GEC) and glomeruli express factor H mRNA and protein. Up-regulated in membranous nephropathy. Likely direct response of GEC to complement attack and may represent protective response. | 12911541 |
| Type | IDs |
|---|---|
| Synonymous | AMBP-1, AMBP1, Fh |
| Gene |
UniProtKB-ID:
Q5XJW6_RAT,
Q91YB6_RAT,
G3V9R2_RAT
UniprotKB:
Q5XJW6,
Q91YB6,
G3V9R2
UniParc:
UPI00000E7E5F,
UPI000019BD96,
UPI0000443F54
EMBL:
CH473958,
BC083174,
AJ320522,
AABR07072332,
AC112858
Ensembl:
ENSRNOG00000030715
KO:
rno:155012
|
| Nucleutide sequences |
EMBL-CDS:
AAH83174.1,
CAC67513.1,
EDM09615.1
Gene_ORFName:
rCG_46221
Ensembl_TRS:
ENSRNOT00000086572,
ENSRNOT00000060111
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000072850,
ENSRNOP00000056859
RefSeq:
NP_569093.2
|
| Others |
UniRef100:
UniRef100_Q5XJW6,
UniRef100_Q91YB6,
UniRef100_G3V9R2
UniRef90:
UniRef90_G3V9R2,
UniRef90_Q5XJW6
UniRef50:
UniRef50_G3V9R2,
UniRef50_Q5XJW6
UniGene:
Rn.101777
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员