CYP2A7 - cytochrome P450 family 2 subfamily A member 7-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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1549 CYP2A7

基因描述

Type	Description
Definition	cytochrome P450 family 2 subfamily A member 7

研究结论

Date	Results	Publications
2020-04-04 12:42:00	Single nucleotide polymorphism in CYP2A7 gene is associated with smoking in whites with Chronic Obstructive Pulmonary Disease.	29767774
2017-08-12 11:14:00	CNV deletion at the CYP2A7 is associated with decreased ovarian cancer risk in BRCA1 carriers.	28145423
2015-12-19 11:07:00	CYP2A7 affects CYP2A6 expression by competing for miR-126* binding.	25710939
2010-01-21 00:00:00	CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism	11960914
2008-03-13 09:02:00	Observational study of genotype prevalence and genetic testing. (HuGE Navigator)	16636685

名称对应

Type	IDs
Synonymous	CPA7, CPAD, CYP2A, CYPIIA7, P450-IIA4
Gene	UniProtKB-ID: CP2A7_HUMAN, F8W816_HUMAN UniprotKB: P20853, F8W816 UniParc: UPI0000160BD9, UPI000013E6D5 EMBL: AC008537, M33317, U22029 Ensembl: ENSG00000198077 KO: hsa:1549
Nucleutide sequences	EMBL-CDS: AAA52138.1, AAB40520.1 Ensembl_TRS: ENST00000301146, ENST00000291764
Protein sequencees	Ensembl_PRO: ENSP00000301146, ENSP00000291764 RefSeq: NP_000755.2, NP_085079.2
Others	UniRef100: UniRef100_P20853, UniRef100_F8W816 UniRef90: UniRef90_P11509 UniRef50: UniRef50_P11509 UniGene: Hs.719890 CCDS: CCDS12569.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29767774	Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls. Nicotine Tob. Res. Sharon M Lutz , Brittni Frederiksen , Ferdouse Begum , Merry-Lynn N McDonald , Michael H Cho , Brian D Hobbs , Margaret M Parker , Dawn L DeMeo , Craig P Hersh , Marissa A Ehringer , Kendra Young , Lai Jiang , Marilyn G Foreman , Greg L Kinney , Barry J Make , David A Lomas , Per Bakke , Amund Gulsvik , James D Crapo , Edwin K Silverman , Terri H Beaty , John E Hokanson , ECLIPSE and COPDGene Investigators	2019-05-21	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
28145423	Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. Eur. J. Hum. Genet. Logan C Walker , Louise Marquart , John F Pearson , George A R Wiggins , Tracy A O'Mara , Michael T Parsons , BCFR , Daniel Barrowdale , Lesley McGuffog , Joe Dennis , Javier Benitez , Thomas P Slavin , Paolo Radice , Debra Frost , EMBRACE , Andrew K Godwin , Alfons Meindl , Rita Katharina Schmutzler , GEMO Study Collaborators , Claudine Isaacs , Beth N Peshkin , Trinidad Caldes , Frans Bl Hogervorst , HEBON , Conxi Lazaro , Anna Jakubowska , Marco Montagna , KConFab Investigators , Xiaoqing Chen , Kenneth Offit , Peter J Hulick , Irene L Andrulis , Annika Lindblom , Robert L Nussbaum , Katherine L Nathanson , Georgia Chenevix-Trench , Antonis C Antoniou , Fergus J Couch , Amanda B Spurdle	2017-04-01	-
25710939	CYP2A7 pseudogene transcript affects CYP2A6 expression in human liver by acting as a decoy for miR-126. Drug Metab. Dispos. Masataka Nakano , Yasunari Fukushima , Shin-ichi Yokota , Tatsuki Fukami , Masataka Takamiya , Yasuhiro Aoki , Tsuyoshi Yokoi , Miki Nakajima	2015-05-01	CYP2A6, CYP2A7, MIR126
22890016	Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract. Respiration Huai-chih Chiang , Chien-Kai Wang , Tsui-Chun Tsou	2012-01-01	CYP2A6, CYP2A7, CYP2A13
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
16636685	CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele. Pharmacogenomics J. T Fukami , M Nakajima , H Sakai , H L McLeod , T Yokoi	2006-04-25	CYP2A6, CYP2A7
15128046	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics David R Nelson , Darryl C Zeldin , Susan M G Hoffman , Lois J Maltais , Hester M Wain , Daniel W Nebert	2004-01-01	Cyp2b26-ps, Cyp2b27-ps, Cyp2d13, CYP4F23P, CYP46A1, CYP4F8, CYP2U1, CYP2R1, CYP4F22, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2A7, CYP2A7P1, CYP3A7, CYP2A13, CYP2B6, CYP2B7P, CYP2C19, CYP2C8, CYP2C9, CYP2C18, CYP2D7, CYP2D6, CYP2D8P, CYP2E1, CYP2F1, CYP2J2, CYP3A4, CYP3A5, CYP4A11, CYP4B1, CYP7A1, CYP8B1, CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP19A1, CYP21A2, CYP24A1, CYP26A1, CYP27A1, CYP51A1, CYP2T3P, CYP4Z2P, CYP2F2P, CYP2T1P, CYP4Z1, CYP2G1P, CYP4X1, CYP4F35P, CYP4A22, CYP4V2, CYP2S1, CYP27C1, CYP26C1, CYP4F24P, CYP4F3, CYP39A1, CYP2W1, CYP26B1, PTGIS, CYP20A1, CYP4F11, CYP3A43, RPL36P16, CYP4F12, TBXAS1, CYP2G2P, CYP4F2, CYP7B1
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
12325023	Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. Hum. Mutat. Mikael Oscarson , Roman A McLellan , Vendela Asp , MariCarmen Ledesma , Maria Luisa Bernal Ruiz , Blanca Sinues , Arja Rautio , Magnus Ingelman-Sundberg	2002-10-01	CYP2A6, CYP2A7

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