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15488 Hsd17b4

15488

Hsd17b4

hydroxysteroid (17-beta) dehydrogenase 4

protein-coding

Mus musculus

基因描述

Type Description
Definition hydroxysteroid (17-beta) dehydrogenase 4

研究结论

Date Results Publications
2020-05-16 10:11:00 The D-bifunctional protein (HSD17B4) and the peroxisomal ABC transporter ABCD3 are essential in peroxisomal oxidation of lauric and palmitic acid. 30540494
2020-03-07 12:29:00 Association of Hsd17b4 with ceramide-enriched mitochondria-associated membranes prevents its interaction with peroxisomal import protein Pex5 at peroxisomes. 31176039
2019-07-20 11:13:00 This study demonstrated that MFP2 deficiency in microglia causes intrinsic dysregulation of their inflammatory profile, which is not harmful to neuronal function, motor function, and cognition in mice during their first year of life 30866963
2018-03-03 11:14:00 Nestin-Mfp2(-/-) mice showed impaired motor learning on the accelerating rotarod and underperformed on the balance beam test 27353294
2016-04-16 11:58:00 Study showed that the resident microglia in Mfp2-/- mice proliferate, are permanently in an activated nonphagocytic state and lose their typical homeostatic markers 25846981

名称对应

Type IDs
Synonymous 17-beta-HSD, 17[b]-HSD, DBP, MFE-2, MFP2, MPF-2, Mfp-2, perMFE-2
Gene
UniProtKB-ID: DHB4_MOUSE
UniprotKB: P51660
UniParc: UPI00000E88B7
EMBL: AK004866, X89998, AK169077, AK088381, AK166801, AK167060, BC022175
Ensembl: ENSMUSG00000024507
KO: mmu:15488
Nucleutide sequences
EMBL-CDS: AAH22175.1, BAE40862.1, CAA62015.1, BAB23627.1, BAC40317.1, BAE39029.1, BAE39222.1
Ensembl_TRS: ENSMUST00000025385
Protein sequencees
Ensembl_PRO: ENSMUSP00000025385
RefSeq: NP_032318.2
Others
UniRef100: UniRef100_P51660
UniRef90: UniRef90_P97852
UniRef50: UniRef50_P51659
UniGene: Mm.277857
CCDS: CCDS29242.1

全选

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