| Type | Description |
|---|---|
| Definition | hydroxysteroid 11-beta dehydrogenase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 11:37:00 | The study presents predicted binding mode of 7-oxygenated 25-hydroxycholesterols in the binding pocket of murine 11HSD2. | 30902677 |
| 2019-06-01 10:22:00 | A subset of HSD2 neurons may promote the dysphoric, anorexic, and anhedonic symptoms of hyperaldosteronism via AgRP-inhibited relay neurons in the parabrachial complex. | 30343334 |
| 2017-08-26 11:49:00 | Kidney-specific deficiency of 11beta-HSD2 leads to Salt-dependent Hypertension, which is attributed to mineralocorticoid receptor-epithelial sodium channel-Na(+)-Cl(-) cotransporter activation in the kidney. | 28559392 |
| 2017-06-10 11:07:00 | Rac1 GTPase regulates 11beta-HSD2 expression, mineralocorticoid receptor activation, and mineralocorticoid receptor-mediated pro-fibrotic signaling. | 28320863 |
| 2017-01-14 11:42:00 | Nr3c2 has a role in mouse skin development in a process that involves HSD11B1/HSD11B2 | 26268211 |
| Type | IDs |
|---|---|
| Synonymous | 11HSD2 |
| Gene |
UniProtKB-ID:
DHI2_MOUSE,
Q6NZB9_MOUSE
UniprotKB:
P51661,
Q6NZB9
UniParc:
UPI000023C834,
UPI00000E7B9F
EMBL:
S79550,
S79552,
X90647,
BC066209,
S79551,
X90646,
S79554,
S79553,
BC014753
Ensembl:
ENSMUSG00000031891
KO:
mmu:15484
|
| Nucleutide sequences |
EMBL-CDS:
CAA62219.1,
AAC60711.1,
AAH14753.1,
CAA62218.1,
AAH66209.1
Ensembl_TRS:
ENSMUST00000034363
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034363
RefSeq:
NP_032315.2
|
| Others |
UniRef100:
UniRef100_Q6NZB9,
UniRef100_P51661
UniRef90:
UniRef90_P50233
UniRef50:
UniRef50_P50233
UniGene:
Mm.5079
CCDS:
CCDS40460.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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