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15483 Hsd11b1

15483

Hsd11b1

hydroxysteroid 11-beta dehydrogenase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition hydroxysteroid 11-beta dehydrogenase 1

研究结论

Date Results Publications
2019-11-16 11:37:00 The formation of 7-keto,25-hydroxycholesterol from 7-ketocholesterol by cholesterol 25-hydroxylase (CH25H) and further stereospecific oxoreduction to 7beta,25-dihydroxycholesterol by human and mouse 11-beta-HSD1 could be demonstrated. 30902677
2019-06-29 12:34:00 tis study shows that 11 beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis 29891135
2019-06-29 10:08:00 These data suggest that 11beta-HSD1 is not crucial for survival of experimental malaria, but alters its progression in a parasite strain-specific manner. 29062028
2018-05-26 10:12:00 exercise training increases pulmonary expression of 11beta-HSD1, thus contributing to local glucocorticoid activation and suppression of pulmonary inflammation in obese mice 28663379
2018-05-19 11:47:00 study demonstrates that glucocorticoid-induced insulin resistance was dependent on 11beta-HSD1, resulting in the critical activation of JNK signaling in adipocytes. 27841334

名称对应

Type IDs
Gene
UniProtKB-ID: DHI1_MOUSE, Q4JHD9_MOUSE
UniprotKB: P50172, Q4JHD9
UniParc: UPI000002146F
EMBL: BC145415, BC138780, AK149518, X83202, DQ089001, S75207, BC132364, X92186
Ensembl: ENSMUSG00000016194
KO: mmu:15483
Nucleutide sequences
EMBL-CDS: CAA63096.1, AAB33601.1, CAA58209.1, AAI38781.1, AAI32365.1, AAI45416.1, BAE28932.1, AAY98349.1
Ensembl_TRS: ENSMUST00000016338, ENSMUST00000161737
Protein sequencees
Ensembl_PRO: ENSMUSP00000125620, ENSMUSP00000016338
RefSeq: XP_030105692.1, XP_006497291.1, NP_001038216.1, NP_032314.2
Others
UniRef100: UniRef100_P50172
UniRef90: UniRef90_P50172
UniRef50: UniRef50_P50172
UniGene: Mm.28328
CCDS: CCDS15635.1

全选

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