| Type | Description |
|---|---|
| Definition | angiomotin |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Angiomotin regulates budding and spread of Ebola virus. | 32381509 |
| 2020-11-21 13:21:00 | AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells. | 31800378 |
| 2020-06-20 11:41:00 | AMOT is primarily expressed in migratory extravillous trophoblast cells (EVTs) and its expression increases after 10 weeks of gestation when oxygen tension rises and EVT migration/invasion peaks. In preeclampsia, however, AMOT expression is decreased and its localization to migratory fetomaternal interface EVTs is disrupted. JMJD6 an oxygen sensor, positively regulates AMOT via oxygen-dependent lysyl hydroxylation. | 30996134 |
| 2020-05-02 10:20:00 | Findings that angiomotin (AMOT)-dependent regulation of Yes-associated protein (YAP) directing human pluripotent stem cells (hPSCs) fate suggest the molecular mechanisms by which the microenvironment can induce neural differentiation. | 31006631 |
| 2020-04-25 11:54:00 | Amot-p130 functions as a tumor suppressor gene in breast cancer, disrupting beta-catenin stability by competing with Axin for binding to tankyrase. | 30792381 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AMOT_HUMAN
UniprotKB:
Q4VCS5
UniParc:
UPI000050ED33,
UPI00000720EE
EMBL:
AF286598,
BC094712,
AB028994,
AY987378
Ensembl:
ENSG00000126016
KO:
hsa:154796
|
| Nucleutide sequences |
EMBL-CDS:
AAG01851.1,
BAA83023.3,
AAH94712.1,
AAY24451.1
Ensembl_TRS:
ENST00000371959,
ENST00000304758,
ENST00000524145
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361027,
ENSP00000305557,
ENSP00000429013
RefSeq:
NP_573572.1,
NP_001373928.1,
XP_016884778.1,
NP_001373927.1,
NP_001106962.1,
XP_005262147.1
|
| Others |
UniRef100:
UniRef100_Q4VCS5
UniRef90:
UniRef90_Q4VCS5
UniRef50:
UniRef50_Q4VCS5
UniGene:
Hs.528051
CCDS:
CCDS14563.1,
CCDS48154.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员