Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.

Cardiovasc. Res.     Christos Tzimas , Daniel M Johnson , Demetrio J Santiago , Elizabeth Vafiadaki , Demetrios A Arvanitis , Constantinos H Davos , Aimilia Varela , Nikolaos C Athanasiadis , Constantinos Dimitriou , Michalis Katsimpoulas , Stephan Sonntag , Mariya Kryzhanovska , Doron Shmerling , Stephan E Lehnart , Karin R Sipido , Evangelia G Kranias , Despina Sanoudou

Characterization of Ca(2+)-Dependent Protein-Protein Interactions within the Ca(2+) Release Units of Cardiac Sarcoplasmic Reticulum.

Mol. Cells     Shilpa Rani , Chang Sik Park , Pradeep Kumar Sreenivasaiah , Do Han Kim

Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.

Cardiovasc. Res.     Bin Liu , Hsiang-Ting Ho , Lucia Brunello , Sathya D Unudurthi , Qing Lou , Andriy E Belevych , Lan Qian , Do Han Kim , Chunghee Cho , Paul M L Janssen , Thomas J Hund , Bjorn C Knollmann , Evangelia G Kranias , Sándor Györke

Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress.

Basic Res. Cardiol.     Chang Sik Park , Shan Chen , Hoyong Lee , Hyeseon Cha , Jae Gyun Oh , Sunghee Hong , Peidong Han , Kenneth S Ginsburg , Sora Jin , Inju Park , Vivek P Singh , Hong-Sheng Wang , Clara Franzini-Armstrong , Woo Jin Park , Donald M Bers , Evangelia G Kranias , Chunghee Cho , Do Han Kim

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase.

Am J Physiol Heart Circ Physiol     Demetrios A Arvanitis , Elizabeth Vafiadaki , Guo-Chang Fan , Bryan A Mitton , Kimberly N Gregory , Federica Del Monte , Aikaterini Kontrogianni-Konstantopoulos , Despina Sanoudou , Evangelia G Kranias

Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein.

Mol. Cell. Biol.     Eric J Jaehnig , Analeah B Heidt , Stephanie B Greene , Ivo Cornelissen , Brian L Black

Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function.

J. Mol. Cell. Cardiol.     Kimberly N Gregory , Kenneth S Ginsburg , Ilona Bodi , Harvey Hahn , Yehia M A Marreez , Qiujing Song , Prabhu A Padmanabhan , Bryan A Mitton , Jason R Waggoner , Federica Del Monte , Woo Jin Park , Gerald W Dorn , Donald M Bers , Evangelia G Kranias

Antisense transcription in the mammalian transcriptome.

Science     S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium

The transcriptional landscape of the mammalian genome.

Science     P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)

Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein.

Biochim. Biophys. Acta     Sunghee Hong , Tae-Wan Kim , Inchul Choi , Jong-Min Woo , Jungsu Oh , Woo Jin Park , Do Han Kim , Chunghee Cho