| Type | Description |
|---|---|
| Definition | hypoxanthine guanine phosphoribosyl transferase |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:10:00 | The authors identified the HPRT-associated purine salvaging pathway as a critical contributor to Adult hematopoietic stem cell fitness in response to stress. Additionally, they provide evidence that the preference for HPRT-associated purine salvaging is unique for Adult hematopoietic stem cells within primitive hematopoietic stem and progenitor cells. | 31574190 |
| 2018-10-06 11:40:00 | The HGprt deficiency in mice is associated with a decrease in colon contractility. | 29305058 |
| 2017-04-22 12:44:00 | This study showed that in HPRT knockout mouse brain did not find any abnormalities change Neurotransmitter and their metabolite concentrations. | 27206901 |
| 2017-02-04 12:02:00 | six metabolites with significantly different contents in wild-type and HPRT-deficient mice, were found. | 27221022 |
| 2014-09-27 12:45:00 | In the HGprt-deficient mouse model, stains for tyrosine hydroxylase (TH) reveal no obvious loss of midbrain dopamine neurons, but quantitative immunoblots reveal reduced TH expression in the striatum. | 24891139 |
| Type | IDs |
|---|---|
| Synonymous | C81579, HPGRT, Hprt1 |
| Gene |
UniProtKB-ID:
HPRT_MOUSE
UniprotKB:
P00493
UniParc:
UPI0000003E3A
EMBL:
BC083145,
K01510,
AK088114,
AK146626,
J00423,
K01507,
K01514,
K01511,
K01508,
K01515,
K01509,
K01512,
K01513,
AK002286
Ensembl:
ENSMUSG00000025630
KO:
mmu:15452
|
| Nucleutide sequences |
EMBL-CDS:
BAE27315.1,
AAA96232.1,
AAA96271.1,
BAC40153.1,
BAB21989.1,
AAH83145.1
Ensembl_TRS:
ENSMUST00000026723
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026723
RefSeq:
NP_038584.2
|
| Others |
UniRef100:
UniRef100_P00493
UniRef90:
UniRef90_P00492
UniRef50:
UniRef50_P00492
UniGene:
Mm.299381
CCDS:
CCDS40972.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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