| Type | Description |
|---|---|
| Definition | hyperphenylalaninemia 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:39:00 | we used the Ang II infused hph-1 mice to examine the roles of NOX isoforms in the development of AAA. We generated double mutants of hph-1-NOX1, hph-1-NOX2, hph-1-p47phox, and hph-1-NOX4 | 27912196 |
| 2015-10-31 11:04:00 | The hph-1 mouse may be a novel tool to investigate the role of BH4 deficiency in anxiety and depression. | 25218564 |
| 2012-11-24 11:01:00 | Reduced tetrahydrobiopterin bioavailability causes endothelial NOS uncoupling, increases superoxide anion production, inhibits eNOS/cGMP signaling, and imposes significant oxidative stress in the cerebral microvasculature. | 22784235 |
| 2010-01-25 11:30:00 | phenylalanine concentration regulates the activity of PAH in the hph-1 mouse and that this acts via a mechanism that includes phosphorylation of the PAH molecule. The kinetic values (K(m) and V(max)) for mouse PAH are also reported. | 19560382 |
| Type | IDs |
|---|---|
| Synonymous | hph-1 |