| Type | Description |
|---|---|
| Definition | homeobox D12 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | early posterior restriction of Hox gene products sets up an anterior-posterior prepattern, which determines the localized activation of Shh; this signal is then translated into digit morphological asymmetry by promoting the late expression of Hoxd genes | 15192229 |
| 2010-01-21 00:00:00 | genes compete for a remote enhancer that recognizes the locus in a polar fashion, with a preference for 5' extremity; modifications in either number or topography of Hoxd loci induced regulatory reallocations affecting both number and morphology of digits | 12432383 |
| 2010-01-21 00:00:00 | point mutation rather than the entire deletion of Hoxd12, such as in knockout and transgenic mice, causes the abnormal limb phenotype in microdactyly mice | 19108020 |
| 2005-06-13 14:20:00 | mutant analysis shows that Hoxd11, Hoxd12, and Hoxd13 genetically interact to form and sculpt the forelimb, a potential genetic milieu that may have been exploited by evolutionary adaptation | 8620844 |
| Type | IDs |
|---|---|
| Synonymous | Hox-4.7, Hox-5.6 |
| Gene |
UniProtKB-ID:
HXD12_MOUSE
UniprotKB:
P23812
UniParc:
UPI00000EAC8F
EMBL:
BC145656,
CH466519,
AL928644,
AK031206,
X58849
Ensembl:
ENSMUSG00000001823
KO:
mmu:15432
|
| Nucleutide sequences |
EMBL-CDS:
AAI45657.1,
EDL27169.1,
BAC27299.1,
CAA41654.1
Ensembl_TRS:
ENSMUST00000001878
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001878
RefSeq:
NP_032300.2
|
| Others |
UniRef100:
UniRef100_P23812
UniRef90:
UniRef90_P23812
UniRef50:
UniRef50_P23812
UniGene:
Mm.57124
CCDS:
CCDS38147.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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