| Type | Description |
|---|---|
| Definition | homeobox B4 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:28:00 | Activated HoxB4-induced hematopoietic stem cells from murine pluripotent stem cells via long-term programming. | 32795499 |
| 2019-02-16 11:37:00 | HOXB4 promoted the formation of hemogenic endothelium cells. | 29456178 |
| 2017-11-25 15:47:00 | Our data reveal a route to establishing functional multipotent HSCs that exploits aspects of in vitro differentiation, transcription factor re-specification with HoxB4 to enhance self-renewal, and Notch-mediated lineage specification | 28009288 |
| 2017-08-26 12:50:00 | can amplify long-term repopulating hematopoietic stem cells in a controlled way. This characteristic depends on a proline-rich sequence near the N terminus, which is unique among HOX genes and highly conserved in higher mammals | 27827825 |
| 2014-12-20 11:02:00 | Data suggest that the homeobox B4 protein (HoxB4) and signal transducer and activator of transcription 3 signals are functionally redundant for hematopoietic stem cells (HSCs) self-renewal rather than exerting independent effects. | 24446131 |
| Type | IDs |
|---|---|
| Synonymous | Hox-2.6 |
| Gene |
UniProtKB-ID:
HXB4_MOUSE
UniprotKB:
P10284
UniParc:
UPI0000026E78
EMBL:
AK133945,
M36654,
BC095947
Ensembl:
ENSMUSG00000038692
KO:
mmu:15412
|
| Nucleutide sequences |
EMBL-CDS:
AAA37848.1,
AAH95947.1,
BAE21943.1
Ensembl_TRS:
ENSMUST00000049241
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048002
RefSeq:
NP_034589.3
|
| Others |
UniRef100:
UniRef100_P10284
UniRef90:
UniRef90_P10284
UniRef50:
UniRef50_P10284
UniGene:
Mm.3546
CCDS:
CCDS25297.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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