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1540 CYLD

1540

CYLD

CYLD lysine 63 deubiquitinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition CYLD lysine 63 deubiquitinase

研究结论

Date Results Publications
2021-02-13 13:23:00 Research on mechanism of miR-130a in regulating autophagy of bladder cancer cells through CYLD. 32862616
2020-12-05 13:01:00 Relationship between clinicopathological characteristics and CYLD expression in patients with cholesteatoma. 33031450
2020-11-21 13:19:00 CYLD dysregulation in pathogenesis of sporadic inclusion body myositis. 31406156
2020-07-11 12:15:00 show here that increased CYLD activity reduces autophagy function, highlighting the importance of autophagy regulation in the pathogenesis of frontotemporal dementia and amyotrophic lateral sclerosis. 32185393
2020-07-04 10:54:00 CYLD marshals the centriolar satellites by deubiquitinating and preventing the E3 ligase Mindbomb 1 (MIB1) from marking PCM1 for proteasomal degradation. 31067453

名称对应

Type IDs
Synonymous BRSS, CDMT, CYLD1, CYLDI, EAC, MFT, MFT1, SBS, TEM, USPL2
Gene
UniProtKB-ID: CYLD_HUMAN, A0A024R6T1_HUMAN
UniprotKB: Q9NQC7, A0A024R6T1
UniParc: UPI0000073A15, UPI000013F1A7
EMBL: AF161542, CH471092, AJ250014, BC012342, AB020656
Ensembl: ENSG00000083799
KO: hsa:1540
Nucleutide sequences
EMBL-CDS: BAA74872.2, AAH12342.1, CAB93533.1, AAF29029.1, EAW82769.1, EAW82770.1, EAW82768.1, EAW82771.1
Gene_ORFName: HSPC057, hCG_1811700
Ensembl_TRS: ENST00000311559, ENST00000569418, ENST00000427738, ENST00000398568, ENST00000564326
Protein sequencees
Ensembl_PRO: ENSP00000454515, ENSP00000381574, ENSP00000308928, ENSP00000457576, ENSP00000392025
RefSeq: NP_001365673.1, XP_016878469.1, NP_056062.1, XP_011521213.1, NP_001365672.1, NP_001035877.1, NP_001365676.1, XP_016878467.1, NP_001365678.1, NP_001365682.1, NP_001365683.1, NP_001365679.1, NP_001365674.1, NP_001035814.1, NP_001365680.1, NP_001365684.1, NP_001365675.1, NP_001365681.1, NP_001365677.1
Others
UniRef100: UniRef100_A0A024R6T1, UniRef100_Q9NQC7
UniRef90: UniRef90_Q9NQC7, UniRef90_Q1RMU2
UniRef50: UniRef50_Q9NQC7
UniGene: Hs.578973
CCDS: CCDS42164.1, CCDS45482.1

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