| Type | Description |
|---|---|
| Definition | homeobox A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:23:00 | A distal enhancer interacting with the Hoxa1 locus through a long-range chromatin loop. Enhancer deletion significantly inhibited expression of RA-induced Hoxa1 and endoderm master control genes. Hoxa1 directly regulates downstream target genes expression and then orchestrates RA-induced early differentiation of ESCs. | 31147716 |
| 2018-07-14 11:04:00 | we provide evidence that HOXA1 displays an unexpectedly long half-life and demonstrate that PRDM14 can reduce the stability and affect the transcriptional activity of HOXA1. | 29471045 |
| 2018-05-05 10:58:00 | Proteomic analyses show that HOXA1 physically interacts on chromatin with PBX, MEIS, and PREP family members, but not with TGIF, suggesting that TGIF may have an independent input into HOXA1-bound regions.This study provides new insight into a regulatory network involving combinatorial interactions between HOXA1 and TALE proteins | 28784834 |
| 2017-12-30 10:10:00 | Hoxa1 and Hoxb1 are required for pharyngeal arch artery development. | 27956219 |
| 2017-12-23 12:56:00 | Authors found evidence for a high degree of evolutionary conservation of many binding regions and downstream targets of Hoxa1 between mouse and zebrafish. | 28982536 |
| Type | IDs |
|---|---|
| Synonymous | ERA1, Hox-1.6 |
| Gene |
UniProtKB-ID:
Q8BNI8_MOUSE,
D3Z4E1_MOUSE,
B9EHK7_MOUSE
UniprotKB:
Q8BNI8,
D3Z4E1,
B9EHK7
UniParc:
UPI00000EB1D1,
UPI00001F3C14,
UPI000024EF90
EMBL:
AK083575,
AC091106,
BC138097
Ensembl:
ENSMUSG00000029844
KO:
mmu:15394
|
| Nucleutide sequences |
EMBL-CDS:
BAC38956.1,
AAI38098.1
Ensembl_TRS:
ENSMUST00000120363,
ENSMUST00000000964
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113724,
ENSMUSP00000000964
RefSeq:
NP_034579.3,
NP_001298047.1
|
| Others |
UniRef100:
UniRef100_P09022,
UniRef100_Q8BNI8,
UniRef100_D3Z4E1
UniRef90:
UniRef90_P49639,
UniRef90_D3Z4E1
UniRef50:
UniRef50_E7ERT8,
UniRef50_P49639
UniGene:
Mm.197
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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