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15382 Hnrnpa1

15382

Hnrnpa1

heterogeneous nuclear ribonucleoprotein A1

protein-coding

Mus musculus

基因描述

Type Description
Definition heterogeneous nuclear ribonucleoprotein A1

研究结论

Date Results Publications
2020-11-21 13:28:00 Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation. 32960212
2020-07-18 10:53:00 these studies suggest that CUG(exp) RNA triggers abnormal expression of multiple nuclear RNA binding proteins, including CELF1 and HNRNPA1, that antagonize MBNL activity to promote fetal splicing patterns 32086392
2019-11-02 12:02:00 Loss of Hnrnpa1 expression leads to dysregulation of cardiac transcription networks and multiple signaling pathways, including BMP, FGF, and Notch in the second heart field. Finally, two rare heterozygous mutations of HNRNPA1 were detected in human congenital heart defects. These findings suggest a role of Hnrnpa1 in embryonic heart development in mice and humans. 29367466
2019-07-20 10:53:00 Report direct role for hnRNPA1 in MYLK alternative splicing in lung endothelial cells. 29077485
2018-11-10 10:49:00 Knockdown of hnRNP A1 led to a decrease in endogenous Nfil3 protein level, which could be due to a reduction in IRES-mediated translation. 28220845

名称对应

Type IDs
Synonymous HDP-1, Hdp, Hnrpa1, hnRNP A1, hnrnp-A1
Gene
UniProtKB-ID: ROA1_MOUSE, Q5EBP8_MOUSE
UniprotKB: P49312, Q5EBP8
UniParc: UPI000016CCFC, UPI0000000C3B, UPI00004CEA26
EMBL: M99167, AK168733, AK161730, BC083136, AK146630, AC164069, BC089340, AK007802, BC080675, AK168420, AK166901, AK166989, AK135391, AK167810, D86728, AK088308, AK167913, AK167161, BC092395, AK131999, AK168531, D86729
Ensembl: ENSMUSG00000046434
KO: mmu:15382
Nucleutide sequences
EMBL-CDS: BAC40273.1, BAA13162.1, AAA37633.1, BAA13161.1, AAH80675.1, BAE40333.1, BAE36552.1, BAB25267.1, BAE20929.1, BAE39302.1, AAH83136.1, BAE39104.1, BAE40409.1, BAE22518.1, BAE39837.1, BAE39920.1, AAH89340.1, BAE27318.1, AAH92395.1, BAE40574.1, BAE39169.1
Ensembl_TRS: ENSMUST00000087351, ENSMUST00000231141, ENSMUST00000230171, ENSMUST00000230489, ENSMUST00000036004
Protein sequencees
Ensembl_PRO: ENSMUSP00000084609, ENSMUSP00000155311, ENSMUSP00000155833, ENSMUSP00000042658, ENSMUSP00000154865
RefSeq: NP_034577.1, NP_001034218.1
Others
UniRef100: UniRef100_P49312, UniRef100_Q5EBP8
UniRef90: UniRef90_P04256, UniRef90_Q5EBP8
UniRef50: UniRef50_P04256
UniGene: Mm.237064, Mm.432031
CCDS: CCDS37233.1

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