| Type | Description |
|---|---|
| Definition | one cut domain, family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 10:29:00 | Loss of Oc1 from the developing pancreatic epithelium resulted in disrupted duct and acinar cell development. | 30831323 |
| 2019-02-23 12:56:00 | Pdx1 and Oc1 cooperativity in Multipotent pancreatic progenitors impacts postnatal beta-cell maturation and function. Here a model of Pdx1-Oc1 double heterozygosity was used to investigate the impact of haploinsufficiency for both of these factors on postnatal beta-cell maturation, function, and adaptability. | 29351489 |
| 2017-10-14 11:27:00 | These results suggest that Oc1 and Pdx1 cooperate prior to their divergence, in pancreatic progenitors, to allow for proper differentiation and functional maturation of beta cells. | 27292642 |
| 2017-07-29 10:07:00 | Expression of motor neuron effector genes is maintained by transient enhancers bound by Isl1/Lhx3 in nascent motor neurons and Isl1/Onecut1 in maturing hypaxial motor neurons. | 27939581 |
| 2017-07-15 11:22:00 | Data show that growth hormone (GH)/lipopolysaccharides (LPS) co-treatment enhanced hepatocyte nuclear factor 6 (Hnf6) expression with corresponding attenuation of apoptosis in WT-derived hepatocytes, but not in KO hepatocytes. | 27936029 |
| Type | IDs |
|---|---|
| Synonymous | D9Ertd423e, HNF-6, Hfh12, Hnf6, Hnf6b, OC-1, Oc1 |
| Gene |
UniProtKB-ID:
HNF6_MOUSE
UniprotKB:
O08755
UniParc:
UPI00000019CF
EMBL:
BC024053,
U95945
Ensembl:
ENSMUSG00000043013
KO:
mmu:15379
|
| Nucleutide sequences |
EMBL-CDS:
AAB53863.1,
AAH24053.1
Ensembl_TRS:
ENSMUST00000056006
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058020
RefSeq:
NP_032288.1
|
| Others |
UniRef100:
UniRef100_O08755
UniRef90:
UniRef90_O08755
UniRef50:
UniRef50_O08755
UniGene:
Mm.303355
CCDS:
CCDS23339.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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