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15369 Hmox2

15369

Hmox2

heme oxygenase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition heme oxygenase 2

研究结论

Date Results Publications
2021-03-13 13:20:00 Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation. 32992485
2020-03-28 10:43:00 Aged male mice are hypersensitive to ischemic acute kidney injury and HO-2 mitigates such sensitivity. This protective effect of HO-2 may be mediated, at least in part, by suppression of phosphorylated signaling. 31215802
2018-12-22 11:01:00 This study demonstrated that HO-2 is involved in reducing inflammatory responses mediated by macrophages. Downstream factors (TNF-alpha, IL1beta and IL-6) that play a role in the TLR4 signaling pathway were suppressed in HO-2 overexpressing macrophages. HO-2 enhanced the survival of allografted skin. 30099287
2018-10-13 10:27:00 Decreased oxygen consumption and increased mitochondrial production in response to hypoxia were dependent upon HO-2 expression. HO-2 expression regulated HIF-1alpha and JNK signaling in a mitochondrial manner. 29849867
2016-10-08 12:44:00 This study demonstrated that Deletion of the heme oxygenase-2 aggravates brain injury following stroma-free hemoglobin-induced 26831741

名称对应

Type IDs
Synonymous HO-2, HO2
Gene
UniProtKB-ID: HMOX2_MOUSE, Q544R7_MOUSE
UniprotKB: O70252, Q544R7
UniParc: UPI000000182D
EMBL: AF054670, BC002011, AK141426, AK134536, AK032175, AF054669, AF029874
Ensembl: ENSMUSG00000004070
KO: mmu:15369
Nucleutide sequences
EMBL-CDS: AAC82363.1, AAH02011.1, AAC82364.1, AAC17981.1, BAE24682.1, BAE22174.1, BAC27744.1
Ensembl_TRS: ENSMUST00000120232, ENSMUST00000118885, ENSMUST00000004172
Protein sequencees
Ensembl_PRO: ENSMUSP00000113110, ENSMUSP00000112397, ENSMUSP00000004172
RefSeq: NP_034573.2, NP_001129538.1, NP_001365928.1, NP_001343979.1
Others
UniRef100: UniRef100_O70252
UniRef90: UniRef90_P23711
UniRef50: UniRef50_P23711
UniGene: Mm.272866
CCDS: CCDS27924.1

全选

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