| Type | Description |
|---|---|
| Definition | iroquois homeobox 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease. | 32422864 |
| 2016-08-13 11:57:00 | IRX2 transcription factor might represent a novel metastasis associated protein that acts as a negative regulator of cellular motility and as a repressor of chemokine expression and loss of IRX2 expression could therefore contribute to early hematogenous dissemination of breast cancer by sustaining chemokine secretion and enabling mobilization of tumor cells. | 26560478 |
| 2016-05-21 13:16:00 | IRX2 modulates the expression levels of MMP2 and VEGF in an AKTdependent manner. | 26062523 |
| 2015-01-17 10:15:00 | The mechanism by which IRX2 promoted cell proliferation and invasion by activating AKT and MMP9 was detected. | 24806332 |
| 2012-05-26 11:30:00 | Results revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2. | 22210879 |
| Type | IDs |
|---|---|
| Synonymous | IRXA2 |
| Gene |
UniProtKB-ID:
IRX2_HUMAN
UniprotKB:
Q9BZI1
UniParc:
UPI00001B6456
EMBL:
AF319967,
AY335940,
AB188492,
BC065189,
AY335939
Ensembl:
ENSG00000170561
KO:
hsa:153572
|
| Nucleutide sequences |
EMBL-CDS:
AAK01202.1,
AAQ16546.1,
AAH65189.1,
BAD37140.1,
AAQ16545.1
Ensembl_TRS:
ENST00000302057,
ENST00000382611
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307006,
ENSP00000372056
RefSeq:
NP_001127694.1,
NP_150366.1,
XP_024310147.1,
XP_011512281.1
|
| Others |
UniRef100:
UniRef100_Q9BZI1
UniRef90:
UniRef90_Q9BZI1
UniRef50:
UniRef50_Q9BZI1
UniGene:
Hs.282089
CCDS:
CCDS3868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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