| Type | Description |
|---|---|
| Definition | serum response factor binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-21 11:59:00 | P49/STRAP expression was increased in the old versus young adult mouse hearts and also increased with advancing population doubling levels in cultured human umbilical vein endothelial cells. The increased expression of p49/STRAP in late life may alter the status of histone acetylation and impact mitochondrial dynamics and thereby reduce mitochondrial function and cardiac performance during mammalian senescence. | 27337995 |
| 2016-05-14 12:35:00 | SRFBP1 is an HCV-specific, pan-genotypic host entry factor. | 26212323 |
| 2010-01-21 00:00:00 | p49/STRAP may be an important SRF cofactor in the transcriptional regulation of mammalian cardiac muscle genes throughout the life span | 15492011 |
| 2010-01-21 00:00:00 | p49/STRAP plays a role in the regulation of intracellular processes such as cardiac cellular metabolism, gene expression, and possibly aging. | 18230186 |
| 2010-01-21 00:00:00 | p49/STRAP can be considered a bona fide co-chaperone of Hsp70. | 19751705 |
| Type | IDs |
|---|---|
| Synonymous | BUD22, P49, Rlb1, STRAP, p49/STRAP |
| Gene |
UniProtKB-ID:
SRFB1_HUMAN
UniprotKB:
Q8NEF9
UniParc:
UPI000006DEC3
EMBL:
BC017102,
AK058015,
CH471086,
BC031222,
AY611630
Ensembl:
ENSG00000151304
KO:
hsa:153443
|
| Nucleutide sequences |
EMBL-CDS:
AAH31222.1,
BAB71631.1,
EAW48900.1,
AAH17102.1,
AAU25829.2
Ensembl_TRS:
ENST00000339397
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341324
RefSeq:
NP_689759.2,
XP_016864600.2
|
| Others |
UniRef100:
UniRef100_Q8NEF9
UniRef90:
UniRef90_Q8NEF9
UniRef50:
UniRef50_Q8NEF9
UniGene:
Hs.107622
CCDS:
CCDS43354.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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