| Type | Description |
|---|---|
| Definition | solute carrier family 38 member 9 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:27:00 | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. | 32868926 |
| 2018-10-13 12:01:00 | Ragulator and SLC38A9 act on the Rag GTPases to activate the mTORC1 pathway in response to nutrient sufficiency. | 30181260 |
| 2017-11-04 11:37:00 | Study validates that SLC38A9 is an arginine sensor for the mTORC1 pathway, and we uncover an unexpectedly central role for SLC38A9 in amino acid homeostasis. SLC38A9 mediates the transport, in an arginine-regulated fashion, of many essential amino acids out of lysosomes, including leucine, which mTORC1 senses through the cytosolic Sestrin proteins. | 29053970 |
| 2015-09-26 12:34:00 | Data suggest that amino acid transporter SLC38A9 controls mTORC1 activity through binding to the Rag-Ragulator complex at the lysosome upon amino acid availability. | 25963655 |
| 2015-06-20 12:14:00 | SLC38A9 is a physical and functional component of the amino acid sensing machinery that controls the activation of mTOR | 25561175 |
| Type | IDs |
|---|---|
| Synonymous | URLC11 |
| Gene |
UniProtKB-ID:
S38A9_HUMAN,
A0A024QZR9_HUMAN,
B3KVK8_HUMAN
UniprotKB:
Q8NBW4,
A0A024QZR9,
B3KVK8
UniParc:
UPI000020C784,
UPI00001403C2,
UPI00003FF92B,
UPI0000D47598,
UPI00004A28F8
EMBL:
AK075190,
BC066891,
BC101362,
AC016632,
CH471123,
AB105188,
AC008784,
BX641065,
AK127988,
AK301850,
AK122957
Ensembl:
ENSG00000177058
KO:
hsa:153129
|
| Nucleutide sequences |
EMBL-CDS:
BAH13566.1,
AAI01363.1,
EAW54926.1,
BAQ19756.1,
BAC11460.1,
CAE46032.1,
BAG54613.1,
AAH66891.1,
EAW54927.1,
EAW54925.1,
EAW54928.1,
BAG53820.1
Gene_ORFName:
hCG_40989,
hCG_40989
Ensembl_TRS:
ENST00000515629,
ENST00000318672,
ENST00000396865,
ENST00000512595,
ENST00000416547
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380074,
ENSP00000316596,
ENSP00000420934,
ENSP00000427335,
ENSP00000397429
RefSeq:
NP_001336312.1,
XP_016864569.1,
XP_011541476.1,
XP_011541482.1,
XP_024310137.1,
XP_016864571.1,
XP_006714602.1,
XP_011541480.1,
XP_011541479.1,
NP_001336313.1,
XP_016864570.1,
XP_016864566.1,
XP_016864567.1,
NP_001245215.1,
NP_001336314.1,
XP_011541478.1,
XP_011541485.1,
NP_001245216.1,
NP_775785.2,
XP_011541486.1,
XP_011541484.1,
NP_001336311.1,
NP_001269358.1
|
| Others |
UniRef100:
UniRef100_Q8NBW4
UniRef90:
UniRef90_Q8NBW4
UniRef50:
UniRef50_Q8NBW4
UniGene:
Hs.745105
CCDS:
CCDS58947.1,
CCDS58948.1,
CCDS3968.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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