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152926 PPM1K

152926

PPM1K

protein phosphatase, Mg2+/Mn2+ dependent 1K

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein phosphatase, Mg2+/Mn2+ dependent 1K

研究结论

Date Results Publications
2019-11-02 13:12:00 three Mg(2+) were located in the active site of the PPM1K N94K instead of two Mg(2+) in the PPM1K wild type 30451284
2018-09-29 11:18:00 Branched chain amino acids related genetic variant rs1440581 was associated with an increased risk of incident T2 Diabetes in a Chinese population. This variant might modify effect of weight gain on development in Insulin resistance. 29855804
2017-09-16 11:18:00 PPM1K rs1440581 may affect changes in glucose metabolism during weight loss, and this effect is dependent on dietary fat and carbohydrate intakes. 28768654
2016-08-20 12:06:00 miR-204 and miR-211 directly repress PPM1K expression via 3'UTR. 26592513
2013-07-06 10:02:00 Overweight people with the C allele of the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 may benefit less in weight loss and improved insulin sensitivity than those without it on a energy-restricted high-fat diet. 23446828

名称对应

Type IDs
Synonymous BDP, MSUDMV, PP2Ckappa, PP2Cm, PTMP, UG0882E07
Gene
UniProtKB-ID: PPM1K_HUMAN
UniprotKB: Q8N3J5
UniParc: UPI00000473F1, UPI00001A843E, UPI00000743B1
EMBL: AY157615, AL834271, AC108213, AK314417, AK054678, BC041350, AY435431, AY994097, BC020850, BC037552, AC107067, CH471057, AF351614, AL834167
Ensembl: ENSG00000163644
KO: hsa:152926
Nucleutide sequences
EMBL-CDS: BAG37038.1, CAD38946.1, AAR06213.1, AAN76514.1, EAX06016.1, AAH20850.1, CAD38869.2, AAO17296.1, AAX77016.1, AAY41021.1, AAH41350.1, BAB70790.1, AAH37552.1
Ensembl_TRS: ENST00000608933
Protein sequencees
Ensembl_PRO: ENSP00000477341
RefSeq: XP_016863294.1, XP_016863296.1, XP_016863295.1, XP_005262832.1, XP_006714174.1, XP_016863293.1, NP_689755.3, XP_016863292.1
Others
UniRef100: UniRef100_Q8N3J5
UniRef90: UniRef90_Q8N3J5
UniRef50: UniRef50_Q8N3J5
UniGene: Hs.43744
CCDS: CCDS3629.1

全选

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