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15285 Mnx1

15285

Mnx1

motor neuron and pancreas homeobox 1

protein-coding

Mus musculus

基因描述

Type Description
Definition motor neuron and pancreas homeobox 1

研究结论

Date Results Publications
2020-05-02 12:03:00 the novel findings of HB9-dependent premature senescence and myeloid-biased perturbed hematopoietic differentiation, for the first time shed light on the oncogenic properties of HB9 in translocation t(7;12) acute myeloid leukemia. 30093397
2018-10-27 11:01:00 excitatory Hb9::Cre-derived interneurons constitute a distinct population of neurons that participates in the rhythm generating kernel for spinal locomotion. 28128321
2016-03-12 10:54:00 Inactivating Mnx1 in embryonic beta-cells (Mnx1(Deltabeta)) caused beta-to-delta-like cell transdifferentiation, which was delayed until postnatal stages; findings identify Mnx1 as an important factor in beta-cell differentiation and proliferation. 26534984
2016-02-20 11:05:00 provide mechanistic insights into the role of phospho-HLXB9 as a pro-oncogenic factor by interacting with a survival factor and by promoting the oncogenic c-Met pathway 26342078
2014-06-14 10:20:00 NKX2-2 and MNX1 are etiological genes for neonatal diabetes. 24411943

名称对应

Type IDs
Synonymous HB9, Hlxb9, MNR2
Gene
UniProtKB-ID: A2RSX2_MOUSE
UniprotKB: A2RSX2
UniParc: UPI000024D87C
EMBL: AC164700, BC132283
Ensembl: ENSMUSG00000001566
KO: mmu:15285
Nucleutide sequences
EMBL-CDS: AAI32284.1
Ensembl_TRS: ENSMUST00000165512
Protein sequencees
Ensembl_PRO: ENSMUSP00000129503
RefSeq: NP_064328.2
Others
UniRef100: UniRef100_A2RSX2
UniRef90: UniRef90_Q9QZW9
UniRef50: UniRef50_P50219
UniGene: Mm.103760

全选

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研究热度

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