| Type | Description |
|---|---|
| Definition | H2.0-like homeobox |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 10:40:00 | HLX is a homeobox transcription factor gene which is relatively conserved across species. Hlx homozygous null mice have a short bowel and reduced muscle cells in the diaphragm, closely resembling the anomalies in the two fetuses and we therefore suggest that the HLX mutation in this family could explain the fetal findings | 28898547 |
| 2017-11-26 00:37:00 | Prdm16 interacts with the transcription factor Hlx, which is stabilized in response to beta3-adrenergic signaling, to increase thermogenic gene expression and mitochondrial biogenesis in subcutaneous WAT. | 28701693 |
| 2015-07-25 11:15:00 | methyl-CpG-binding domain protein 2 (MBD2), an epigenetic regulator, controls autoimmunity and EAE through T-bet/Hlx. | 24934598 |
| 2014-08-30 10:05:00 | Hlx regulates sprouting in vitro, but its role in sprouting is nonessential in vivo. HLX is regulated by shear stress and a subtle defect in vascular remodeling is present in knockout embryos. | 24764455 |
| 2012-06-30 11:50:00 | Results shown that over-expressed Hlx in DC2.4 up-regulated the transcription and expression of IFN-gamma, increased the expression of maturation makers including CD40, CD80, CD86, MHC-I and MHC-II | 22483852 |
| Type | IDs |
|---|---|
| Synonymous | Hlx1 |
| Gene |
UniProtKB-ID:
HLX_MOUSE,
Q80YV1_MOUSE,
Q549B7_MOUSE,
Q6P3B7_MOUSE
UniprotKB:
Q61670,
Q80YV1,
Q549B7,
Q6P3B7
UniParc:
UPI000018CDD5,
UPI000022832E,
UPI0000000918
EMBL:
BC050146,
X58250,
AF172318,
AK154090,
BC064068
Ensembl:
ENSMUSG00000039377
KO:
mmu:15284
|
| Nucleutide sequences |
EMBL-CDS:
CAA41204.1,
AAH50146.1,
AAG22584.1,
BAE32368.1,
AAH64068.1
Ensembl_TRS:
ENSMUST00000048572
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040505
RefSeq:
NP_032276.1
|
| Others |
UniRef100:
UniRef100_Q61670,
UniRef100_Q6P3B7
UniRef90:
UniRef90_Q61670
UniRef50:
UniRef50_Q14774
UniGene:
Mm.1347
CCDS:
CCDS15593.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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