| Type | Description |
|---|---|
| Definition | homeodomain interacting protein kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice. | 31582725 |
| 2020-08-15 19:03:00 | IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion. | 31387937 |
| 2020-07-25 10:31:00 | The loss of HIPK2 increases cytosolic and mitochondrial Parkin protein levels under basal conditions and upon exposure to mitochondrial toxins, which protect mitochondria from toxin-induced damage | 31776210 |
| 2020-06-27 11:09:00 | EGFR drives the progression of acute kidney injury to chronic kidney disease through HIPK2 overexpression. | 31131063 |
| 2020-06-20 11:23:00 | these findings suggest that CM-HIPK2 is required to maintain normal cardiac function via extracellular signal-regulated kinase signaling. | 31581792 |
| Type | IDs |
|---|---|
| Synonymous | 1110014O20Rik, B230339E18Rik, Stank |
| Gene |
UniProtKB-ID:
HIPK2_MOUSE,
A0A0R4J202_MOUSE,
Q5D0E9_MOUSE,
A0A0R4J204_MOUSE
UniprotKB:
Q9QZR5,
A0A0R4J202,
Q5D0E9,
A0A0R4J204
UniParc:
UPI000016C927,
UPI00004E194A,
UPI00000E7717,
UPI00000E7859,
UPI0000020CBF,
UPI0000001523,
UPI000002A097
EMBL:
AC161147,
AC154016,
AK019821,
AF333792,
AC118613,
BC031904,
AF333791,
AF273680,
AK016742,
AF077659,
AF170302,
AF170301,
AF208292
Ensembl:
ENSMUSG00000061436
KO:
mmu:15258
|
| Nucleutide sequences |
EMBL-CDS:
AAG02078.1,
BAB30405.1,
AAC63011.1,
AAK07650.1,
AAD52567.1,
AAD52566.1,
AAG41237.1,
BAB31866.1,
AAK07649.1,
AAH31904.1
Ensembl_TRS:
ENSMUST00000161779,
ENSMUST00000162359,
ENSMUST00000160360,
ENSMUST00000160962
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125150,
ENSMUSP00000124133,
ENSMUSP00000125500,
ENSMUSP00000125572
RefSeq:
NP_001281073.1,
NP_001129537.1,
XP_006505666.1,
XP_006505665.1,
NP_034563.2,
NP_001281072.1
|
| Others |
UniRef100:
UniRef100_Q5D0E9,
UniRef100_Q9QZR5,
UniRef100_A0A0R4J202
UniRef90:
UniRef90_A0A0R4J202,
UniRef90_Q9QZR5
UniRef50:
UniRef50_Q9QZR5,
UniRef50_H0XA39
UniGene:
Mm.23790,
Mm.391962,
Mm.486937
CCDS:
CCDS20017.2,
CCDS80527.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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