| Type | Description |
|---|---|
| Definition | homeodomain interacting protein kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 10:08:00 | The miR-200c/141 cluster regulated breast cancer stem cells heterogeneity and promoted the epithelial-mesenchymal transformation-like breast cancer stem cells generation, which resulted in increased tumor metastasis and inhibited tumor growth by directly upregulating the target gene homeodomain-interacting protein kinase 1 (HIPK1) and sequential beta-catenin activation. | 30613263 |
| 2013-02-02 11:28:00 | Therefore, our data confirm that the beta-Catenin signaling plays a dual role in controlling cell proliferation/differentiation in the brain and indicate that Hipk1 is the crucial interactor able to revert the outcome of beta-Catenin signaling in cells. | 22095214 |
| 2012-09-01 11:06:00 | Despite the expanded marginal zone B cell population in the HIPK1(-/-) mice, the T-independent type 2 humoral response was impaired. | 22545114 |
| 2010-01-21 00:00:00 | The present study indicated the overlapping roles for Hipk1 and Hipk2 in mediating cell proliferation and apoptosis in response to morphogenetic and genotoxic signals during mouse development. | 16537918 |
| 2010-01-21 00:00:00 | SENP1 mediates TNF-induced desumoylation and translocation of HIPK1, leading to an enhanced ASK1-dependent apoptosis. | 18219322 |
| Type | IDs |
|---|---|
| Synonymous | 1110062K04Rik, Myak |
| Gene |
UniProtKB-ID:
HIPK1_MOUSE
UniprotKB:
O88904
UniParc:
UPI00000E6DF9,
UPI00004E1949,
UPI0000054C7B
EMBL:
AK122333,
AF170303,
BC145697,
BC145699,
AF077658,
AF071071,
AF170304,
AF071070
Ensembl:
ENSMUSG00000008730
KO:
mmu:15257
|
| Nucleutide sequences |
EMBL-CDS:
AAI45700.1,
AAD41592.1,
AAD41593.1,
AAI45698.1,
AAD52569.1,
BAC65615.1,
AAD52568.1,
AAC63010.1
Ensembl_TRS:
ENSMUST00000118317,
ENSMUST00000106845,
ENSMUST00000029438
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102458,
ENSMUSP00000113998,
ENSMUSP00000029438
RefSeq:
NP_001288233.1,
XP_011238326.1,
XP_036018798.1,
NP_001288235.1,
NP_034562.2
|
| Others |
UniRef100:
UniRef100_O88904
UniRef90:
UniRef90_Q86Z02
UniRef50:
UniRef50_Q86Z02
UniGene:
Mm.20827
CCDS:
CCDS79992.1,
CCDS38576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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