| Type | Description |
|---|---|
| Definition | hematopoietically expressed homeobox |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:25:00 | Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a. | 32090320 |
| 2020-12-12 13:22:00 | The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development. | 32601467 |
| 2020-04-04 12:26:00 | The homeodomain and N-terminal repression domain of Hhex were critical for inhibiting Foxp3 and other Treg signature genes. Thus, Hhex plays an essential role in inhibiting Treg cell differentiation and function via inhibition of Foxp3. | 31792183 |
| 2018-04-21 11:57:00 | Hematopoietic stem cells require Hhex to promote PRC2-mediated Cdkn2a repression to enable continued self-renewal and response to hematopoietic stress. | 28577303 |
| 2017-06-10 11:26:00 | The Hhex evolutionarily conserved non-coding region appears to be a core node for the convergence of the transcription factor network that governs the emergence of Hematopoietic stem cells. | 28189604 |
| Type | IDs |
|---|---|
| Synonymous | Hex, Hex1, Hhex-rs2, Prh, Prhx |
| Gene |
UniProtKB-ID:
HHEX_MOUSE
UniprotKB:
P43120
UniParc:
UPI0000000297
EMBL:
AK014111,
AF132550,
AK033664,
Z21524,
BC057986,
AB017132
Ensembl:
ENSMUSG00000024986,
ENSMUSG00000111314
KO:
mmu:15242
|
| Nucleutide sequences |
EMBL-CDS:
AAF04349.1,
CAA79729.1,
BAC28416.1,
AAH57986.1,
BAB29163.1,
BAA76714.1
Ensembl_TRS:
ENSMUST00000025944,
ENSMUST00000213879
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025944,
ENSMUSP00000150958
RefSeq:
NP_032271.1
|
| Others |
UniRef100:
UniRef100_P43120
UniRef90:
UniRef90_P43120
UniRef50:
UniRef50_P43120
UniGene:
Mm.33896
CCDS:
CCDS29778.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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