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15233 Hgd

15233

Hgd

homogentisate 1, 2-dioxygenase

protein-coding

Mus musculus

基因描述

Type Description
Definition homogentisate 1, 2-dioxygenase

研究结论

Date Results Publications
2020-06-06 12:20:00 HGD knockout mouse exhibits the characteristic traits of alkaptonuria (AK)U. Both adult and embryo HGD expression has been localized to the liver and kidney only. More importantly, the conditional Hgd tm1d MxCre model has highlighted the importance of liver HGD expression in limiting the pathological effects of the HGA pool despite apparent reabsorption of homogentisic acid in the kidney. 31600782

名称对应

Type IDs
Synonymous Hgo, aku
Gene
UniProtKB-ID: HGD_MOUSE
UniprotKB: O09173
UniParc: UPI00001B2E08
EMBL: BC055029, U58988, CH466521
Ensembl: ENSMUSG00000022821
KO: mmu:15233
Nucleutide sequences
EMBL-CDS: AAC53224.1, EDK97961.1, AAH55029.1
Ensembl_TRS: ENSMUST00000160847
Protein sequencees
Ensembl_PRO: ENSMUSP00000125492
RefSeq: NP_038575.2, XP_030104838.1
Others
UniRef100: UniRef100_O09173
UniRef90: UniRef90_O09173
UniRef50: UniRef50_Q93099
UniGene: Mm.157442
CCDS: CCDS49849.1

全选

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