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1522 CTSZ

1522

CTSZ

cathepsin Z

protein-coding

Homo sapiens

基因描述

Type Description
Definition cathepsin Z

研究结论

Date Results Publications
2020-08-01 14:54:00 our present study revealed that KMT2A epigenetically promotes cancer progression by targeting CTSZ, which has specific functions in cancer invasion and metastasis. 31090199
2019-11-30 12:55:00 CTSZ polymorphisms are associated with jaundice-stage progression in primary biliary cholangitis. 29795304
2019-10-26 11:33:00 results indicate that altered expression and localization of cathepsin Z in hepatocytes are characteristic features of primary biliary cholangitis (PBC) and other cholestatic liver diseases, and are implicated in the progression of PBC. 30087368
2019-09-21 12:33:00 Deguelin inhibits the activation of CtsZ downstream FAK/Src/Paxillin signaling. 30018008
2018-11-24 12:20:00 expression of cathepsin B and X was detected in stromal cells and cancer cells throughout the glioblastoma (GBM) sections, whereas cathepsin K expression was more restricted to arteriole-rich regions in the GBM sections. Metabolic mapping showed that cathepsin B, but not cathepsin K is active in GSC niches. 30046941

名称对应

Type IDs
Synonymous CTSX
Gene
UniProtKB-ID: CATZ_HUMAN
UniprotKB: Q9UBR2
UniParc: UPI000000D9CC
EMBL: AF073890, AF136275, BC042168, AF009923, CH471077, AF136274, AK314931, AF136276, AF032906, AF136273, AL109840
Ensembl: ENSG00000101160
KO: hsa:1522
Nucleutide sequences
EMBL-CDS: AAC63141.1, EAW75448.1, AAH42168.1, AAF13145.1, AAC39839.1, BAG37437.1, AAF13148.1, AAC61477.1
Ensembl_TRS: ENST00000217131
Protein sequencees
Ensembl_PRO: ENSP00000217131
RefSeq: NP_001327.2
Others
UniRef100: UniRef100_Q9UBR2
UniRef90: UniRef90_Q9UBR2
UniRef50: UniRef50_Q9UBR2
UniGene: Hs.252549
CCDS: CCDS13474.1

全选

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