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15212 Hexb

15212

Hexb

hexosaminidase B

protein-coding

Mus musculus

基因描述

Type Description
Definition hexosaminidase B

研究结论

Date Results Publications
2014-10-25 11:43:00 mast cell granule beta-hexosaminidase is crucial for defense against bacterial invasion, but is not involved in the allergic response. the bactericidal mechanism of beta-hexosaminidase involves degradation of bacterial cell wall peptidoglycan. 25015817
2013-01-05 10:55:00 transgenic inducible strains of Sandhoff disease mice provide a dynamic platform with which to explore the pathophysiological sequelae immediately after loss of neuronal lysosomal beta-hexosaminidase activity. 23028353
2012-01-21 10:48:00 Thymic involution and corticosterone level in Sandhoff disease model mice. 21598013
2010-08-09 11:46:00 These data suggest that the restricted ketogenic diet and N-butyldeoxynojirimycin may be a potential combinatorial therapy for Sandhoff disease. 20374428
2010-01-21 00:00:00 There was no change in the level of GM2 storage and pro-apoptotic activity or astrocyte activation in HexB-/- knockout mice 18657867

名称对应

Type IDs
Gene
UniProtKB-ID: HEXB_MOUSE, Q3TXR9_MOUSE
UniprotKB: P20060, Q3TXR9
UniParc: UPI0000021C95
EMBL: Y00964, U07727, U07037, U07046, U07049, AK159134, U07737, AK151149, U07039, U07722, U07740, AK159178, U07043, AK160560, U07723, U07038, U07725, U07728, U07042, U07040, U07738, U07741, U07044, U07739, AK168825, U07041, U07048, U07724, U07633, U07742, U07047, U07045, U07036, U07726
Ensembl: ENSMUSG00000021665
KO: mmu:15212
Nucleutide sequences
EMBL-CDS: AAB60667.1, CAA68781.1, AAA18776.1, AAA74738.1, BAE34877.1, BAE30155.1, BAE35874.1, BAE40652.1, BAE34846.1
Ensembl_TRS: ENSMUST00000022169
Protein sequencees
Ensembl_PRO: ENSMUSP00000022169
RefSeq: NP_034552.1
Others
UniRef100: UniRef100_P20060
UniRef90: UniRef90_P20060
UniRef50: UniRef50_P20060
UniGene: Mm.27816
CCDS: CCDS26709.1

全选

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