| Type | Description |
|---|---|
| Definition | homeobox gene expressed in ES cells |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 10:51:00 | our data provide evidence for a novel role of Hesx1 in the control of self-renewal and maintenance of the undifferentiated state in ESCs and mouse embryos. | 31761678 |
| 2015-11-14 11:29:00 | Hesx1 plays a significant role in sustaining pluripotency in embryonic stem cells.Hesx1 transcriptionally suppresses differentiation-related genes. | 26188092 |
| 2014-11-08 11:54:00 | Wnt inhibition during the first day has larger impact on the activation of Hesx1 and Six3, suggesting that in embryos Wnt inhibition caused by Dkk1 contributes greatly in the establishment of the anterior forebrain precursor. | 24520934 |
| 2014-06-21 11:37:00 | Variability in Hes1 expression therefore helps to explain why responsiveness varies between individual ES cells, and this in turn helps to explain why pluripotent cells commit to differentiate asynchronously.. | 23649667 |
| 2011-12-24 10:27:00 | Transcriptional profiling of anterior forebrain precursors from mouse embryos expressing eGFP from the Hesx1 locus provides molecular evidence supporting a novel function of Hesx1 in mediating repression of Wnt/beta-catenin target activation. | 22007134 |
| Type | IDs |
|---|---|
| Synonymous | HES-1, Rpx |
| Gene |
UniProtKB-ID:
HESX1_MOUSE
UniprotKB:
Q61658
UniParc:
UPI0000023BF3
EMBL:
BC145262,
X80040,
AC124603,
BC132053,
BC132051,
AK082831,
U40720
Ensembl:
ENSMUSG00000040726
KO:
mmu:15209
|
| Nucleutide sequences |
EMBL-CDS:
BAC38643.1,
AAA97869.1,
AAI45263.1,
AAI32054.1,
AAI32052.1,
CAA56344.1
Ensembl_TRS:
ENSMUST00000035433,
ENSMUST00000224331
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041999,
ENSMUSP00000152952
RefSeq:
NP_034550.2,
XP_006518633.1
|
| Others |
UniRef100:
UniRef100_Q61658
UniRef90:
UniRef90_Q61658
UniRef50:
UniRef50_Q61658
UniGene:
Mm.4802
CCDS:
CCDS26884.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员