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15208 Hes5

15208

Hes5

hes family bHLH transcription factor 5

protein-coding

Mus musculus

基因描述

Type Description
Definition hes family bHLH transcription factor 5

研究结论

Date Results Publications
2019-09-07 10:15:00 This increases the decoding capacity of HES5 oscillations and correlates with interneuron versus motor neuron cell fate. 31249377
2019-03-23 11:30:00 Olig2 represses expression of the Notch signaling pathway effectors Hes1 and Hes5 29389974
2018-08-18 10:48:00 These results suggest that hyperhomocysteinemia-enhanced brain damage is associated with increased autophagy and neuronal apoptosis in Apo E(-/-) mice, in which downregulation of hes1 and hes5 is involved. 29171783
2018-07-28 10:56:00 Although Hes5-GFP and Hes1 are coexpressed in particular developmental contexts, we also noted cohorts of lens or retinal cells expressing just one factor. The dynamic Hes5-GFP expression pattern, coupled with its derepressed expression in Hes1 mutants, suggests that this transgene contains the relevant cis-regulatory elements that regulate endogenous Hes5 in the mouse lens and retina. 28675662
2018-05-05 12:00:00 Hes5 is expressed in the nascent mesoderm of gastrulating mouse embryos. Hes5 knockdown enhances primitive erythropoiesis in mouse embryonic stem cells. A stage-specific pulse of Hes5 instructs preferential cardiac fate in mouse embryonic stem cells. 28648899

名称对应

Type IDs
Synonymous bHLHb38
Gene
UniProtKB-ID: HES5_MOUSE, Q499J8_MOUSE
UniprotKB: P70120, Q499J8
UniParc: UPI0000004181
EMBL: BC099865, BC099863, AK078170, BC099864, AK139390, BC103539, D32132, AK087508
Ensembl: ENSMUSG00000048001
KO: mmu:15208
Nucleutide sequences
EMBL-CDS: BAA06858.1, BAC39904.1, BAC37159.1, AAH99863.1, AAH99865.1, AAH99864.1, AAI03540.1, BAE23990.1
Ensembl_TRS: ENSMUST00000049621
Protein sequencees
Ensembl_PRO: ENSMUSP00000051118
RefSeq: NP_034549.1, XP_006538625.3, NP_001357684.1
Others
UniRef100: UniRef100_P70120
UniRef90: UniRef90_P70120
UniRef50: UniRef50_P70120
UniGene: Mm.137268
CCDS: CCDS19018.1

全选

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