| Type | Description |
|---|---|
| Definition | protein phosphatase, Mg2+/Mn2+ dependent 1L |
| Date | Results | Publications |
|---|---|---|
| 2012-12-08 11:21:00 | identified ACBD3 as an interacting partner of PPM1L, and showed that this association, which recruits PPM1L to ER-Golgi membrane contact sites, is mediated by a GOLD (Golgi dynamics) domain in ACBD3 | 22796112 |
| 2010-06-30 22:07:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-03-01 11:59:00 | Genetic variation at chromosome 3 harbors an element that regulates expression of an upstream candidate tumor suppressor, PPM1L, thus providing a novel mechanism for colorectal tumorigenesis. | 19847890 |
| 2010-01-21 00:00:00 | CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus. | 18165232 |
| 2010-01-21 00:00:00 | These results suggest that PP2Cepsilon maintains ASK1 in an inactive state by dephosphorylation in quiescent cells, supporting the possibility that PP2Cepsilon and PP5 play different roles in H2O2-induced regulation of ASK1 activity. | 17456047 |
| Type | IDs |
|---|---|
| Synonymous | PP2C-epsilon, PP2CE, PPM1-LIKE |
| Gene |
UniProtKB-ID:
PPM1L_HUMAN
UniprotKB:
Q5SGD2
UniParc:
UPI000068425D,
UPI000153D988,
UPI000006DE9E,
UPI000046F91B
EMBL:
BC104885,
AK055115,
BC110801,
AY337264,
BC104887
Ensembl:
ENSG00000163590
KO:
hsa:151742
|
| Nucleutide sequences |
EMBL-CDS:
BAB70856.1,
AAI04888.1,
AAI04886.1,
AAR00269.1
Ensembl_TRS:
ENST00000497343,
ENST00000464260,
ENST00000498165,
ENST00000295839
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295839,
ENSP00000417659,
ENSP00000420746,
ENSP00000420354
RefSeq:
NP_001304840.1,
XP_011510742.1,
NP_640338.2,
NP_001304841.1
|
| Others |
UniRef100:
UniRef100_Q5SGD2
UniRef90:
UniRef90_Q8BHN0
UniRef50:
UniRef50_Q8BHN0
UniGene:
Hs.389027
CCDS:
CCDS82869.1,
CCDS33886.1,
CCDS82868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员