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15161 Hcfc1

15161

Hcfc1

host cell factor C1

protein-coding

Mus musculus

基因描述

Type Description
Definition host cell factor C1

研究结论

Date Results Publications
2020-04-04 10:42:00 In the brain, HCF-1 is important for organ development and cell proliferation. 31207118
2018-09-01 10:39:00 These studies indicate HCF-1 is critical for glucocorticoid receptor activation of the viral immediate early genes and suggests that glucocorticoid induction of viral reactivation proceeds via an HCF-1- glucocorticoid receptor mechanism in the absence of the viral immediate early activator VP16. 29899098
2017-06-03 11:38:00 male epiblast-specific loss of Hcfc1 leads to a developmental arrest at E6.5 with a rapid progressive cell-cycle exit and an associated failure of anterior visceral endoderm migration and primitive streak formation. 27521049
2017-05-27 11:04:00 Beyond its well-known role in adding beta-O-GlcNAc to serine and threonine residues of nuclear and cytoplasmic proteins, OGT also acts as a protease in the maturation of the cell cycle regulator, HCF-1, and serves as an integral member of several protein complexes, many of them linked to gene expression. (Review) 27294441
2016-08-27 11:07:00 survival of the heterozygous Hcfc1(epiKO/+) female embryos llustrates the developmental plasticity of the post-implantation mouse embryo - in this instance, permitting survival of females heterozygous for an X-linked embryonic lethal allele 26921005

名称对应

Type IDs
Synonymous AW060991, HCF, HCF1
Gene
UniProtKB-ID: HCFC1_MOUSE, B1AUX2_MOUSE
UniprotKB: Q61191, B1AUX2
UniParc: UPI0000193243, UPI0000EE0589
EMBL: U53925, AK088827, AL672002, AJ627036, U80821, BC053742, CH466650
Ensembl: ENSMUSG00000031386
KO: mmu:15161
Nucleutide sequences
EMBL-CDS: AAB01163.1, EDL29851.1, BAC40597.1, CAF25305.1, AAD09225.1, AAH53742.1
Ensembl_TRS: ENSMUST00000033761, ENSMUST00000114372
Protein sequencees
Ensembl_PRO: ENSMUSP00000033761, ENSMUSP00000110012
RefSeq: NP_032250.2, XP_006527898.1, XP_017173876.1, XP_006527899.1
Others
UniRef100: UniRef100_B1AUX2, UniRef100_Q61191
UniRef90: UniRef90_Q61191, UniRef90_B1AUX2
UniRef50: UniRef50_P51610
UniGene: Mm.439140, Mm.491126
CCDS: CCDS30218.1

全选

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