| Type | Description |
|---|---|
| Definition | growth differentiation factor 7 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 13:46:00 | BMP-12 activates tenogenic pathway in human adipose stem cells. | 28214472 |
| 2017-01-28 11:16:00 | The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk. | 26783083 |
| 2015-03-28 11:06:00 | closest protein-coding genes were respectively GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108), which encodes a transcription factor that regulates esophageal and cardiac development | 25447851 |
| 2014-06-21 13:07:00 | BMP12 induces tenogenic differentiation of adipose-derived stromal cells via the Smad1/5/8 pathway. | 24155967 |
| 2011-11-05 12:50:00 | studies show that even though tenogenic (BMP 12 and BMP 13) and osteogenic (BMP2) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers | 21702718 |
| Type | IDs |
|---|---|
| Synonymous | BMP12 |
| Gene |
UniProtKB-ID:
GDF7_HUMAN,
Q75RY1_HUMAN
UniprotKB:
Q7Z4P5,
Q75RY1
UniParc:
UPI0000232F01,
UPI0000208B29
EMBL:
AF522369,
AC012065,
AB158468
Ensembl:
ENSG00000143869
KO:
hsa:151449
|
| Nucleutide sequences |
EMBL-CDS:
AAP97720.1,
BAD07014.1
Ensembl_TRS:
ENST00000272224
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000272224
RefSeq:
NP_878248.2
|
| Others |
UniRef100:
UniRef100_Q75RY1,
UniRef100_Q7Z4P5
UniRef90:
UniRef90_Q7Z4P5
UniRef50:
UniRef50_Q7Z4P5
UniGene:
Hs.447688
CCDS:
CCDS1701.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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