| Type | Description |
|---|---|
| Definition | hemolytic complement |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | [Complement 5a regulates the function of dendritic cells to induce pathogenic polarization of regulatory T cell/helper T cell 17 in sepsis]. | 33565394 |
| 2020-07-11 12:30:00 | Evidence for a pivotal role of the C5a/C5aR1 axis in propagating renal injury in the development of diabetic kidney disease (DKD) by disrupting mitochondrial agility, thereby establishing a new immunometabolic signaling pathway in DKD. | 31624141 |
| 2020-02-29 10:08:00 | data provide in vivo modeling evidence that gain-of-function changes in complement C3 drive Atypical hemolytic uremic syndrome. They also show that long-term C5 deficiency is not accompanied by development of other renal complications (such as C3 glomerulopathy) despite sustained dysregulation of C3. | 30714990 |
| 2020-02-22 12:19:00 | Irrespective of the genetic defect, adenoviral delivery of C5 improved insulin sensitivity in both C5cont and C5def mice, indicating an insulin-sensitizing function of C5. | 31084499 |
| 2020-02-01 11:28:00 | Generation of C5a during the effector phase of house dust mite-induced allergic lung inflammation contributes to TH2 cell differentiation and airway hyper-responsiveness without impacting ILC2 cells. | 31340811 |
| Type | IDs |
|---|---|
| Synonymous | C5, C5a, He, Hfib2 |
| Gene |
UniProtKB-ID:
CO5_MOUSE
UniprotKB:
P06684
UniParc:
UPI000002919D
EMBL:
M35526,
AL845534,
M35525
Ensembl:
ENSMUSG00000026874
KO:
mmu:15139
|
| Nucleutide sequences |
EMBL-CDS:
AAA37348.1,
AAA37349.1
Ensembl_TRS:
ENSMUST00000028233
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028233
RefSeq:
NP_034536.3,
XP_017171158.1
|
| Others |
UniRef100:
UniRef100_P06684
UniRef90:
UniRef90_P06684
UniRef50:
UniRef50_P01031
UniGene:
Mm.2168
CCDS:
CCDS15957.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员