| Type | Description |
|---|---|
| Definition | G protein-coupled bile acid receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:28:00 | Overexpression of TGR5 alleviates myocardial ischemia/reperfusion injury via AKT/GSK-3beta mediated inflammation and mitochondrial pathway. | 31909787 |
| 2021-03-13 13:23:00 | Structural basis of GPBAR activation and bile acid recognition. | 32698187 |
| 2021-02-20 13:35:00 | Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects. | 32747812 |
| 2021-01-09 13:25:00 | Decreased Expression of TGR5 in Vogt-Koyanagi-Harada (VKH) Disease. | 30794473 |
| 2020-12-19 13:46:00 | Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the beta-catenin destruction complex. | 31930324 |
| Type | IDs |
|---|---|
| Synonymous | BG37, GPCR19, GPR131, M-BAR, TGR5 |
| Gene |
UniProtKB-ID:
GPBAR_HUMAN
UniprotKB:
Q8TDU6
UniParc:
UPI000000D72D
EMBL:
BC033625,
AK122658,
CH471063,
AB086170,
AB083601,
AB089307,
AK122660
Ensembl:
ENSG00000179921
KO:
hsa:151306
|
| Nucleutide sequences |
EMBL-CDS:
BAG53647.1,
BAB89314.1,
BAC65343.1,
AAH33625.1,
BAG53648.1,
EAW70598.1,
BAC55235.1
Ensembl_TRS:
ENST00000522678,
ENST00000479077,
ENST00000521462,
ENST00000519574
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000430202,
ENSP00000430698,
ENSP00000430886,
ENSP00000428824
RefSeq:
XP_011509045.1,
XP_016858958.1,
NP_001308879.1,
NP_001070662.1,
NP_733800.1,
XP_016858957.1,
XP_016858956.1,
NP_001070659.1
|
| Others |
UniRef100:
UniRef100_Q8TDU6
UniRef90:
UniRef90_Q8TDU6
UniRef50:
UniRef50_Q8TDU6
UniGene:
Hs.160954
CCDS:
CCDS46515.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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