| Type | Description |
|---|---|
| Definition | pseudouridine synthase 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:46:00 | PUS10 differentially participates in the metabolic pathways of miRNA and tRNA. In the nucleus, PUS10 promotes miRNA biogenesis via interaction with pri-miRNA.In the cytoplasm, PUS10 modifies tRNA, and its pseudouridylation activity is required for cell growth. | 31819270 |
| 2018-06-09 10:56:00 | The caspase-3-mediated movement of PUS10 and the release of mitochondrial contents enhancing caspase-3 activity creates a feedback amplification loop for caspase-3 action. Therefore, any defect in the movement or interactions of PUS10 would reduce the TRAIL sensitivity of tumor cells. | 28981101 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 21072187 |
| 2010-06-30 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20468071 |
| 2010-01-21 00:00:00 | crystal structure of Pus10 (previously denoted as FLJ32312) at 2.0 A resolution and modeling studies describe protein domains and active sites | 17900615 |
| Type | IDs |
|---|---|
| Synonymous | CCDC139, DOBI |
| Gene |
UniProtKB-ID:
PUS10_HUMAN,
A8K6R4_HUMAN
UniprotKB:
Q3MIT2,
A8K6R4
UniParc:
UPI00015DA8E4,
UPI000013E1F4
EMBL:
AK056874,
CH471053,
BC101706,
AL832208,
BC101680,
AK291729
Ensembl:
ENSG00000162927
KO:
hsa:150962
|
| Nucleutide sequences |
EMBL-CDS:
AAI01707.1,
BAB71300.1,
AAI01681.1,
CAI46123.1,
EAX00024.1,
BAF84418.1
Ensembl_TRS:
ENST00000407787,
ENST00000316752
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326003,
ENSP00000386074
RefSeq:
XP_024308488.1,
XP_011530873.1,
XP_011530878.1,
XP_011530872.1,
XP_016858918.1,
XP_016858917.1,
NP_001309056.1,
NP_001309052.1,
XP_011530876.1,
XP_011530870.1,
XP_011530875.1,
XP_011530880.1,
NP_653310.2,
NP_001309053.1
|
| Others |
UniRef100:
UniRef100_Q3MIT2,
UniRef100_A8K6R4
UniRef90:
UniRef90_Q3MIT2
UniRef50:
UniRef50_Q3MIT2
UniGene:
Hs.368348
CCDS:
CCDS1865.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31819270 |
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation. Nat Chem Biol Jinghui Song , Yuan Zhuang , Chenxu Zhu , Haowei Meng , Bo Lu , Bingteng Xie , Jinying Peng , Mo Li , Chengqi Yi |
2020-02-01 | - |
| 30530625 |
RNA Manisha Deogharia , Shaoni Mukhopadhyay , Archi Joardar , Ramesh Gupta |
2019-03-01 | - |
| 29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
| 28981101 |
Cell Death Dis Sujata Jana , Andrew C Hsieh , Ramesh Gupta |
2017-10-05 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 23128233 |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature Luke Jostins , Stephan Ripke , Rinse K Weersma , Richard H Duerr , Dermot P McGovern , Ken Y Hui , James C Lee , L Philip Schumm , Yashoda Sharma , Carl A Anderson , Jonah Essers , Mitja Mitrovic , Kaida Ning , Isabelle Cleynen , Emilie Theatre , Sarah L Spain , Soumya Raychaudhuri , Philippe Goyette , Zhi Wei , Clara Abraham , Jean-Paul Achkar , Tariq Ahmad , Leila Amininejad , Ashwin N Ananthakrishnan , Vibeke Andersen , Jane M Andrews , Leonard Baidoo , Tobias Balschun , Peter A Bampton , Alain Bitton , Gabrielle Boucher , Stephan Brand , Carsten Büning , Ariella Cohain , Sven Cichon , Mauro D'Amato , Dirk De Jong , Kathy L Devaney , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Lynnette R Ferguson , Denis Franchimont , Karin Fransen , Richard Gearry , Michel Georges , Christian Gieger , Jürgen Glas , Talin Haritunians , Ailsa Hart , Chris Hawkey , Matija Hedl , Xinli Hu , Tom H Karlsen , Limas Kupcinskas , Subra Kugathasan , Anna Latiano , Debby Laukens , Ian C Lawrance , Charlie W Lees , Edouard Louis , Gillian Mahy , John Mansfield , Angharad R Morgan , Craig Mowat , William Newman , Orazio Palmieri , Cyriel Y Ponsioen , Uros Potocnik , Natalie J Prescott , Miguel Regueiro , Jerome I Rotter , Richard K Russell , Jeremy D Sanderson , Miquel Sans , Jack Satsangi , Stefan Schreiber , Lisa A Simms , Jurgita Sventoraityte , Stephan R Targan , Kent D Taylor , Mark Tremelling , Hein W Verspaget , Martine De Vos , Cisca Wijmenga , David C Wilson , Juliane Winkelmann , Ramnik J Xavier , Sebastian Zeissig , Bin Zhang , Clarence K Zhang , Hongyu Zhao , International IBD Genetics Consortium (IIBDGC) , Mark S Silverberg , Vito Annese , Hakon Hakonarson , Steven R Brant , Graham Radford-Smith , Christopher G Mathew , John D Rioux , Eric E Schadt , Mark J Daly , Andre Franke , Miles Parkes , Severine Vermeire , Jeffrey C Barrett , Judy H Cho |
2012-11-01 | - |
| 22412388 |
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet. Eimear E Kenny , Itsik Pe'er , Amir Karban , Laurie Ozelius , Adele A Mitchell , Sok Meng Ng , Monica Erazo , Harry Ostrer , Clara Abraham , Maria T Abreu , Gil Atzmon , Nir Barzilai , Steven R Brant , Susan Bressman , Edward R Burns , Yehuda Chowers , Lorraine N Clark , Ariel Darvasi , Dana Doheny , Richard H Duerr , Rami Eliakim , Nir Giladi , Peter K Gregersen , Hakon Hakonarson , Michelle R Jones , Karen Marder , Dermot P B McGovern , Jennifer Mulle , Avi Orr-Urtreger , Deborah D Proctor , Ann Pulver , Jerome I Rotter , Mark S Silverberg , Thomas Ullman , Stephen T Warren , Matti Waterman , Wei Zhang , Aviv Bergman , Lloyd Mayer , Seymour Katz , Robert J Desnick , Judy H Cho , Inga Peter |
2012-01-01 |
LINC00492,
LINC01475,
PRG3,
UBD,
SNX20,
SLCO6A1,
COX15,
IL23R,
PUS10,
CYLD,
RDH10,
SBSPON,
NKX2-3,
TMEM17,
ZNF365,
SLC35D1,
EHBP1,
ACSL6,
GABBR1,
TCERG1L,
SERBP1,
CNNM1,
CPAMD8,
GOT1,
SLC43A3,
HLA-A,
HLA-F,
HLA-G,
HLA-H,
C2orf74,
IL3,
IL12RB2,
INPP5D,
C1orf141,
MOG,
AK3,
CUTC,
PEX13,
ATG16L1,
USP40,
PRG2,
PSMB10,
ENTPD7,
PTGER4,
REL,
RPL7,
SAG,
CCL1,
CCL2,
CCL7,
CCL8,
CCL11,
CCL13,
NOD2,
PAPOLG,
SLC22A4,
SCARNA5,
TERF1,
KCNH6,
SLC25A28,
KIAA1841,
ADO,
DGKD,
NKD1,
PDLIM4,
P4HA2,
KCNB2,
USP34
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员